Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

por Amine Meliani, Florence Boisgerault, Romain Hardet, Solenne Marmier, Fanny Collaud, Giuseppe Ronzitti, Christian Leborgne, Helena Costa Verdera, Marcelo Simon Sola, Severine Charles, Alban Vignaud, Laetitia van Wittenberghe, Giorgia Manni, Olivier Christophe, Francesca Fallarino, Christopher Roy, Alicia Michaud, Petr Ilyinskii, Takashi Kei Kishimoto, Federico Mingozzi
Publicado 2018

A switchable self-assembling and disassembling chiral system based on a porphyrin-substituted phenylalanine–phenylalanine motif

por Georgios Charalambidis, Evangelos Georgilis, Manas K. Panda, Christopher E. Anson, Annie K. Powell, Stephen Doyle, David Moss, Tobias Jochum, Peter N. Horton, Simon J. Coles, Mathieu Linares, David Beljonne, Jean-Valère Naubron, Jonas Conradt, Heinz Kalt, Anna Mitraki, Athanassios G. Coutsolelos, Teodor Silviu Balaban
Publicado 2016

Modulating supramolecular binding of carbon dioxide in a redox-active porous metal-organic framework

por Zhenzhong Lu, Harry G. W. Godfrey, Ivan da Silva, Yongqiang Cheng, Mathew Savage, Floriana Tuna, Eric J. L. McInnes, Simon J. Teat, Kevin J. Gagnon, Mark D. Frogley, Pascal Manuel, Svemir Rudić, Anibal J. Ramirez-Cuesta, Timothy L. Easun, Sihai Yang, Martin Schröder
Publicado 2017

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

por Simon Schroeder, Christin Mache, Hannah Kleine-Weber, Victor M. Corman, Doreen Muth, Anja Richter, Diana Fatykhova, Ziad A. Memish, Megan L. Stanifer, Steeve Boulant, Mitra Gultom, Ronald Dijkman, Stephan Eggeling, Andreas Hocke, Stefan Hippenstiel, Volker Thiel, Stefan Pöhlmann, Thorsten Wolff, Marcel A. Müller, Christian Drosten
Publicado 2021

Changes in notifiable infectious disease incidence in China during the COVID-19 pandemic

por Meng-Jie Geng, Hai-Yang Zhang, Lin-Jie Yu, Chen-Long Lv, Tao Wang, Tian-Le Che, Qiang Xu, Bao-Gui Jiang, Jin-Jin Chen, Simon I. Hay, Zhong-Jie Li, George F. Gao, Li-Ping Wang, Yang Yang, Li-Qun Fang, Wei Liu
Publicado 2021

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis

por Grigory Ryzhakov, Nathaniel R. West, Fanny Franchini, Simon Clare, Nicholas E. Ilott, Stephen N. Sansom, Samuel J. Bullers, Claire Pearson, Alice Costain, Alun Vaughan-Jackson, Jeremy A. Goettel, Joerg Ermann, Bruce H. Horwitz, Ludovico Buti, Xin Lu, Subhankar Mukhopadhyay, Scott B. Snapper, Fiona Powrie
Publicado 2018

A cautionary perspective regarding the isolation and serial propagation of SARS-CoV-2 in Vero cells

por Simon G. P. Funnell, Babak Afrough, John James Baczenas, Neil Berry, Kevin R. Bewley, Rebecca Bradford, Clint Florence, Yann Le Duff, Mark Lewis, Ryan V. Moriarty, Shelby L. O. Connor, Karen L. Osman, Steven Pullan, Sujatha Rashid, Kevin S. Richards, Kimberly J. Stemple, Ivana Knezevic
Publicado 2021

Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study.

por Ian W Rodger, Dorothy Dilar, Janet Dwyer, John Bienenstock, Andu Coret, Judith Coret-Simon, Gary Foster, Arlene Franchetto, Slobodan Franic, Charles H Goldsmith, David Koff, Norman B Konyer, Mitchell Levine, Ellen McDonald, Michael D Noseworthy, John Paulseth, Luciana Ribeiro, Mary Jane Sayles, Lehana Thabane
Publicado 2013

Methotrexate Treatment of Newly Diagnosed RA Patients Is Associated With DNA Methylation Differences at Genes Relevant for Disease Pathogenesis and Pharmacological Action

por Kari Guderud, Kari Guderud, Line H. Sunde, Line H. Sunde, Siri T. Flåm, Siri T. Flåm, Marthe T. Mæhlen, Maria D. Mjaavatten, Ellen S. Norli, Ida M. Evenrød, Bettina K. Andreassen, Sören Franzenburg, Andre Franke, Simon Rayner, Kristina Gervin, Kristina Gervin, Kristina Gervin, Benedicte A. Lie, Benedicte A. Lie
Publicado 2021

Evaluation of the interaction between insecticide resistance-associated genes and malaria transmission in Anopheles gambiae sensu lato in central Côte d’Ivoire

por Rosine Z. Wolie, Alphonsine A. Koffi, Ludovic P. Ahoua Alou, Eleanore D. Sternberg, Oulo N’Nan-Alla, Amal Dahounto, Florent H. A. Yapo, Kpahe M. H. Kanh, Soromane Camara, Welbeck A. Oumbouke, Innocent Z. Tia, Simon-Pierre A. Nguetta, Matthew B. Thomas, Raphael NGuessan
Publicado 2021

The effectiveness of alcohol screening and brief intervention in emergency departments: a multicentre pragmatic cluster randomized controlled trial.

por Colin Drummond, Paolo Deluca, Simon Coulton, Martin Bland, Paul Cassidy, Mike Crawford, Veronica Dale, Eilish Gilvarry, Christine Godfrey, Nick Heather, Ruth McGovern, Judy Myles, Dorothy Newbury-Birch, Adenekan Oyefeso, Steve Parrott, Robert Patton, Katherine Perryman, Tom Phillips, Jonathan Shepherd, Robin Touquet, Eileen Kaner
Publicado 2014

Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults

por Elissavet Nikolaou, Simon P. Jochems, Elena Mitsi, Sherin Pojar, Annie Blizard, Jesus Reiné, Carla Solórzano, Edessa Negera, Beatriz Carniel, Alessandra Soares-Schanoski, Victoria Connor, Hugh Adler, Seher R. Zaidi, Caz Hales, Helen Hill, Angie Hyder-Wright, Stephen B. Gordon, Jamie Rylance, Daniela M. Ferreira
Publicado 2021

Dietary triggers of gut inflammation following exclusive enteral nutrition in children with Crohn’s disease: a pilot study

por Konstantinos Gkikas, Michael Logan, Ben Nichols, Umer Z. Ijaz, Clare M. Clark, Vaios Svolos, Lisa Gervais, Hazel Duncan, Vikki Garrick, Lee Curtis, Elaine Buchanan, Tracey Cardigan, Lawrence Armstrong, Caroline Delahunty, Diana M. Flynn, Andrew R. Barclay, Rachel Tayler, Simon Milling, Richard Hansen, Richard K. Russell, Konstantinos Gerasimidis
Publicado 2021

Schistosome infection in Senegal is associated with different spatial extents of risk and ecological drivers for Schistosoma haematobium and S. mansoni.

por Isabel J Jones, Susanne H Sokolow, Andrew J Chamberlin, Andrea J Lund, Nicolas Jouanard, Lydie Bandagny, Raphaël Ndione, Simon Senghor, Anne-Marie Schacht, Gilles Riveau, Skylar R Hopkins, Jason R Rohr, Justin V Remais, Kevin D Lafferty, Armand M Kuris, Chelsea L Wood, Giulio De Leo
Publicado 2021

Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer

por Rosario I. Corona, Ji-Heui Seo, Xianzhi Lin, Dennis J. Hazelett, Jessica Reddy, Marcos A. S. Fonseca, Forough Abassi, Yvonne G. Lin, Paulette Y. Mhawech-Fauceglia, Sohrab P. Shah, David G. Huntsman, Alexander Gusev, Beth Y. Karlan, Benjamin P. Berman, Matthew L. Freedman, Simon A. Gayther, Kate Lawrenson
Publicado 2020

Stochastic models support rapid peopling of Late Pleistocene Sahul

por Corey J. A. Bradshaw, Kasih Norman, Sean Ulm, Alan N. Williams, Chris Clarkson, Joël Chadœuf, Sam C. Lin, Zenobia Jacobs, Richard G. Roberts, Michael I. Bird, Laura S. Weyrich, Simon G. Haberle, Sue O’Connor, Bastien Llamas, Tim J. Cohen, Tobias Friedrich, Peter Veth, Matthew Leavesley, Frédérik Saltré
Publicado 2021

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation

por Pauline Scholler, Damien Nevoltris, Dimitri de Bundel, Simon Bossi, David Moreno-Delgado, Xavier Rovira, Thor C. Møller, Driss El Moustaine, Michaël Mathieu, Emilie Blanc, Heather McLean, Elodie Dupuis, Gérard Mathis, Eric Trinquet, Hervé Daniel, Emmanuel Valjent, Daniel Baty, Patrick Chames, Philippe Rondard, Jean-Philippe Pin
Publicado 2017

Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

por Giada Zurlo, Xijuan Liu, Mamoru Takada, Cheng Fan, Jeremy M. Simon, Travis S. Ptacek, Javier Rodriguez, Alex von Kriegsheim, Juan Liu, Jason W. Locasale, Adam Robinson, Jing Zhang, Jessica M. Holler, Baek Kim, Marie Zikánová, Jörgen Bierau, Ling Xie, Xian Chen, Mingjie Li, Charles M. Perou, Qing Zhang
Publicado 2019

Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements

por Fiona Allum, Åsa K. Hedman, Xiaojian Shao, Warren A. Cheung, Jinchu Vijay, Frédéric Guénard, Tony Kwan, Marie-Michelle Simon, Bing Ge, Cristiano Moura, Elodie Boulier, Lars Rönnblom, Sasha Bernatsky, Mark Lathrop, Mark I. McCarthy, Panos Deloukas, André Tchernof, Tomi Pastinen, Marie-Claude Vohl, Elin Grundberg
Publicado 2019

The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress

por Michael Bauer, Zuzana Nascakova, Anca-Irina Mihai, Phil F. Cheng, Mitchell P. Levesque, Simon Lampart, Robert Hurwitz, Lennart Pfannkuch, Jana Dobrovolna, Melanie Jacobs, Sina Bartfeld, Anders Dohlman, Xiling Shen, Alevtina A. Gall, Nina R. Salama, Antonia Töpfer, Achim Weber, Thomas F. Meyer, Pavel Janscak, Anne Müller
Publicado 2020