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  1. 39221
    Refining the Balance of Attenuation and Immunogenicity of Respiratory Syncytial Virus by Targeted Codon Deoptimization of Virulence Genes
    “... are the most clinically advanced in children, but achieving an optimal balance of attenuation...”
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  2. 39222
    Sequence Diversity in the <italic toggle="yes">pe_pgrs</italic> Genes of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Is Independent of Human T Cell Recognition
    “... pe_pgrs genes in 94 clinical strains from five phylogenetic lineages of the M. tuberculosis complex (MTBC...”
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  3. 39223
    Efficient and Scalable Precision Genome Editing in <italic toggle="yes">Staphylococcus aureus</italic> through Conditional Recombineering and CRISPR/Cas9-Mediated Counterselection
    “... of 3 tested) and primary clinical isolates (6 of 6 tested), typically yielding thousands...”
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  4. 39224
    Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells
    “... to cause relapsing infections and antibiotic treatment failure in various clinical setups. Previous studies...”
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  5. 39225
    Diagnosis of Zika Virus Infection by Peptide Array and Enzyme-Linked Immunosorbent Assay
    “.... These assays may be useful in guiding clinical management of mothers at risk for potential exposure to ZIKV...”
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  6. 39226
    The F-Box Protein Fbp1 Shapes the Immunogenic Potential of <italic toggle="yes">Cryptococcus neoformans</italic>
    “... that the activity of F-box protein 1 (Fbp1) in highly virulent C. neoformans clinical strain H99 shapes its...”
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  7. 39227
    Deciphering MCR-2 Colistin Resistance
    “... clinical therapeutics targeting severe infections by MCR-2-containing pathogens. IMPORTANCE Carbapenem...”
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  8. 39228
    The In-Feed Antibiotic Carbadox Induces Phage Gene Transcription in the Swine Gut Microbiome
    “... in bacteria of clinical importance. Interestingly, the present study shows greater prophage gene expression...”
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  9. 39229
    Binding of NAD<sup>+</sup>-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A <italic toggle="yes">Streptococcus</italic>
    “... in NADase that render it catalytically inactive can be detected in clinical isolates, including invasive...”
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  10. 39230
    Evolution of Invasion in a Diverse Set of <italic toggle="yes">Fusobacterium</italic> Species
    “...ABSTRACT The diverse Fusobacterium genus contains species implicated in multiple clinical...”
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  11. 39231
    Genomic Evidence for a Globally Distributed, Bimodal Population in the Ovine Footrot Pathogen <named-content content-type="genus-species">Dichelobacter nodosus</named-content>
    “.... Depending on the virulence of the infective bacterial strain, clinical signs vary from a mild interdigital...”
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  12. 39232
    High-Resolution Transcriptomic Analysis of the Adaptive Response of <named-content content-type="genus-species">Staphylococcus aureus</named-content> during Acute and Chronic Phases of Osteomyelitis
    “... by quantitative reverse transcription-PCR (qRT-PCR) of a subset of these in vivo-expressed genes in clinical...”
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  13. 39233
    Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A <italic toggle="yes">Streptococcus</italic> Survival in Macrophages
    “.... These findings may explain the nearly universal production of SLO by GAS clinical isolates and the association...”
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  14. 39234
    Live Attenuated Influenza Vaccine Enhances Colonization of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> and <named-content content-type="genus-species">Staphylococcus aureus</named-content> in Mice
    “... of the clinically important bacterial pathogens Streptococcus pneumoniae (serotypes 19F and 7F) and Staphylococcus...”
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  15. 39235
    Intra-Amniotic Infection with <italic toggle="yes">Ureaplasma parvum</italic> Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment with Clarithromycin
    “... parvum is the most common bacterium found in this clinical condition. Next, using animal models, we...”
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  16. 39236
    Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection
    “... clinical symptoms, increased retention of corneal sensitivity, and decreased infiltrating leukocytes...”
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  17. 39237
    An Experimental Group A <italic toggle="yes">Streptococcus</italic> Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model
    “... colonization and clinical symptoms of pharyngitis and tonsillitis. We have tested the efficacy...”
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  18. 39238
    Rapid Replacement of <named-content content-type="genus-species">Acinetobacter baumannii</named-content> Strains Accompanied by Changes in Lipooligosaccharide Loci and Resistance Gene Repertoire
    “.... Extensive sequencing of clinical isolates from one hospital spanning a decade and a second hospital...”
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  19. 39239
    <named-content content-type="genus-species">Bordetella pertussis</named-content> Can Be Motile and Express Flagellum-Like Structures
    “... and found that both laboratory-adapted strains and clinical isolates can be motile. Upon isolation of motile...”
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  20. 39240
    Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments
    “... increases the overall efficiency of LASV entry and infection. IMPORTANCE Lassa virus is the most clinically...”
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