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  1. 40361
    <italic toggle="yes">SLC6A14</italic> Is a Genetic Modifier of Cystic Fibrosis That Regulates <italic toggle="yes">Pseudomonas aeruginosa</italic> Attachment to Human Bronchial Epithelial Cells
    “.... IMPORTANCE CF patients with shared CFTR gene mutations show significant variability in their clinical...”
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  2. 40362
    <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> Biofilm Formation Is Strain Dependent, Multifactorial, and Associated with Reduced Invasiveness and Immunoreactivity during Colonization
    “... that the morphology of biofilms formed by both invasive and noninvasive clinical isolates in vivo is distinct from...”
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  3. 40363
    The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue
    “... in clinically relevant models. Here, we demonstrate that an early virus isolate from the recent A(H7N9) outbreak...”
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  4. 40364
    Influenza Virus A/Anhui/1/2013 (H7N9) Replicates Efficiently in the Upper and Lower Respiratory Tracts of Cynomolgus Macaques
    “... on clinical aspects of disease, radiographic, histological, and gene expression profile changes in the upper...”
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  5. 40365
    Plasmids Shaped the Recent Emergence of the Major Nosocomial Pathogen <named-content content-type="genus-species">Enterococcus faecium</named-content>
    “... present the first comprehensive population-wide analysis of the pan-plasmidome of a clinically important...”
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  6. 40366
    CARD9 Is Required for Classical Macrophage Activation and the Induction of Protective Immunity against Pulmonary Cryptococcosis
    “.... Consequently, clinical and animal studies indicate that CARD9 is an important regulator of protective immunity...”
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  7. 40367
    A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene
    “... in strain 13 and Hartley guinea pigs, as reflected by the absence of detectable clinical signs in animals...”
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  8. 40368
    Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to <italic toggle="yes">Candida</italic> Species
    “... warn of the potential infectious complications arising from the recent clinical development of novel...”
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  9. 40369
    The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in <italic toggle="yes">Aspergillus fumigatus</italic>
    “... of clinically approved echinocandin drugs to treat invasive aspergillosis by blocking β-1,3-glucan synthase...”
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  10. 40370
    AtrR Is an Essential Determinant of Azole Resistance in <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
    “...A promoter that is associated with alleles of this gene conferring clinically important azole...”
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  11. 40371
    Structural and Regulatory Changes in PBP4 Trigger Decreased β-Lactam Susceptibility in <named-content content-type="genus-species">Enterococcus faecalis</named-content>
    “... therapeutics capable of inhibiting clinical enterococcal strains....”
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  12. 40372
    Antibodies against the Majority Subunit (PilA) of the Type IV Pilus of Nontypeable <named-content content-type="genus-species">Haemophilus influenzae</named-content> Disperse <named-content content-type="genus-species">Moraxella catarrhalis</named-content> from a Dual-Species Biofilm
    “...) and Moraxella catarrhalis (Mcat) frequently cocultured from clinical specimens. Bacterial biofilms in the middle...”
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  13. 40373
    Forward Genetic Dissection of Biofilm Development by <named-content content-type="genus-species">Fusobacterium nucleatum</named-content>: Novel Functions of Cell Division Proteins FtsX and EnvC
    “... of basic cellular processes in this clinically significant pathogen....”
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  14. 40374
    Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages
    “... virus challenge. These candidate vaccines are now being manufactured for clinical evaluation....”
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  15. 40375
    A Class 1 Histone Deacetylase with Potential as an Antifungal Target
    “... of RpdA. Upcoming analyses of clinically approved and novel inhibitors will elucidate their therapeutic...”
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  16. 40376
    Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious <named-content content-type="genus-species">Staphylococcus aureus</named-content> Disease
    “... against Staphylococcus aureus targeting single antigens have failed in clinical trials despite positive...”
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  17. 40377
    Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children
    “... of the pathophysiology of CM would allow the development of adjunctive therapies to improve clinical outcomes. A hallmark...”
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  18. 40378
    The ClpX and ClpP2 Orthologs of <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Perform Discrete and Essential Functions in Organism Growth and Development
    “... the importance of the chlamydial Clp proteins to this clinically important bacterium. Additionally, our study...”
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  19. 40379
    Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of <named-content content-type="genus-species">Escherichia coli</named-content> in a Manner Controlled by YhdP
    “... surface antigen made by all members of Enterobacteriaceae, including many clinically relevant genera (e.g...”
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  20. 40380
    Population Analysis of <named-content content-type="genus-species">Staphylococcus aureus</named-content> Reveals a Cryptic, Highly Prevalent Superantigen SElW That Contributes to the Pathogenesis of Bacteremia
    “... epidemic clone. Deletion of selw in a representative CC398 clinical isolate, S. aureus NM001, resulted...”
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