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  1. 5761
    In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19
    “...Abstract In the genome of SARS-CoV-2, the 5′-terminus encodes a polyprotein, which is further...”
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  2. 5762
    Tumor infiltrating lymphocyte clusters are associated with response to immune checkpoint inhibition in BRAF V600 E/K mutated malignant melanomas
    “...), even more pronounced within the sub-cohort of BRAF V600 E/K -mutated MM patients (AUC = 0.7, n = 32...”
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  3. 5763
    SHANK2 mutations impair apoptosis, proliferation and neurite outgrowth during early neuronal differentiation in SH-SY5Y cells
    “... obtained SH-SY5Y cell lines with frameshift mutations on one or both SHANK2 alleles. We investigated...”
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  4. 5764
    Collagen V insufficiency in a mouse model for Ehlers Danlos-syndrome affects viscoelastic biomechanical properties explaining thin and brittle corneas
    “...-conditioning cycle, a stress-relaxation test and a rupture test. In a total of 28 eyes from a Col5a1 +/− mouse...”
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  5. 5765
    Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients
    “... that decreased expression of microRNA-425-5p in men and decreased expression of microRNA-451 in women were...”
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  6. 5766
    Single-cell transcriptome of bronchoalveolar lavage fluid reveals sequential change of macrophages during SARS-CoV-2 infection in ferrets
    “...A longitudinal analysis of SARS-CoV-2 infection in humans is challenging. Here the authors show a...”
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  7. 5767
    Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’
    “...High resolution characterisation of the virus specific T cell response to SARS CoV2 provides...”
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  8. 5768
    Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria
    “... of CCR5+ monocyte-derived dendritic cells from the spleen to the brains of Plasmodium bergheiANKA...”
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  9. 5769
    FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress
    “... or by using competing antibodies directed against the α5 and β1 integrin subunits. These short-term...”
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  10. 5770
    D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile
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  11. 5771
    Computational design of SARS-CoV-2 peptide binders with better predicted binding affinities than human ACE2 receptor
    “...Abstract SARS-CoV-2 is coronavirus causing COVID-19 pandemic. To enter human cells, receptor...”
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  12. 5772
    Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization
    “... and maintenance of immune homeostasis, while its association with susceptibility and severity of SARS-CoV-2...”
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  13. 5773
    Genetic characteristics and pathogenesis of H5 low pathogenic avian influenza viruses from wild birds and domestic ducks in South Korea
    “...Abstract H5 and H7 subtypes of low pathogenic avian influenza viruses (LPAIVs) can mutate to highly...”
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  14. 5774
    Comprehensive virtual screening of 4.8 k flavonoids reveals novel insights into allosteric inhibition of SARS-CoV-2 MPRO
    “...Abstract SARS-CoV-2 main protease is a common target for inhibition assays due to its high...”
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  15. 5775
    Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2
    por Chia-Ming Su, Leyi Wang, Dongwan Yoo
    Publicado 2021
    “...Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent...”
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  16. 5776
    Author Correction: NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes
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  17. 5777
    MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats
    por Feng X, Hu J, Zhan F, Luo D, Hua F, Xu G
    Publicado 2021
    Materias: “...microrna-138-5p...”
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  18. 5778
    Physalins V-IX, 16,24-cyclo-13,14-seco withanolides from Physalis angulata and their antiproliferative and anti-inflammatory activities
    “...Abstract Five new physalins, including a novel 1,10-seco one, physalin V (1), a tricarboxylic acid...”
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  19. 5779
    Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases
    “... of hematological disorders. Eculizumab, an anti-complement C5 monoclonal antibody, is the current standard of care...”
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  20. 5780
    Genome-scale analysis identifies NEK2, DLGAP5 and ECT2 as promising diagnostic and prognostic biomarkers in human lung cancer
    “... samples, were used to discover differentially expressed genes (DEGs). NEK2, DLGAP5 and ECT2 were found...”
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