SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion

por Eunkyung Lie, Ji Seung Ko, Su-Yeon Choi, Junyeop Daniel Roh, Yi Sul Cho, Ran Noh, Doyoun Kim, Yan Li, Hyeyeon Kang, Tae-Yong Choi, Jungyong Nam, Won Mah, Dongmin Lee, Seong-Gyu Lee, Ho Min Kim, Hyun Kim, Se-Young Choi, Ji Won Um, Myoung-Goo Kang, Yong Chul Bae, Jaewon Ko, Eunjoon Kim
Publicado 2016

Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction

por Kathryn L. Post, Manuel Belmadani, Payel Ganguly, Fabian Meili, Riki Dingwall, Troy A. McDiarmid, Warren M. Meyers, Caitlin Herrington, Barry P. Young, Daniel B. Callaghan, Sanja Rogic, Matthew Edwards, Ana Niciforovic, Alessandro Cau, Catharine H. Rankin, Timothy P. O’Connor, Shernaz X. Bamji, Christopher J. R. Loewen, Douglas W. Allan, Paul Pavlidis, Kurt Haas
Publicado 2020

Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

por Michel Bernier, Dylan Harney, Yen Chin Koay, Antonio Diaz, Abhishek Singh, Devin Wahl, Tamara Pulpitel, Ahmed Ali, Vince Guiterrez, Sarah J. Mitchell, Eun-Young Kim, John Mach, Nathan L. Price, Miguel A. Aon, David G. LeCouteur, Victoria C. Cogger, Carlos Fernandez-Hernando, John O’Sullivan, Mark Larance, Ana Maria Cuervo, Rafael de Cabo
Publicado 2020

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

por Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Wardak, Lung-Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessene, John Silke, Peter E. Czabotar, Andrew I. Webb, James M. Murphy
Publicado 2018

Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

por Eunee Lee, Seungjoon Lee, Jae Jin Shin, Woochul Choi, Changuk Chung, Suho Lee, Jihye Kim, Seungmin Ha, Ryunhee Kim, Taesun Yoo, Ye-Eun Yoo, Jisoo Kim, Young Woo Noh, Issac Rhim, Soo Yeon Lee, Woohyun Kim, Taekyung Lee, Hyogeun Shin, Il-Joo Cho, Karl Deisseroth, Sang Jeong Kim, Joo Min Park, Min Whan Jung, Se-Bum Paik, Eunjoon Kim
Publicado 2021

A catalogue of biochemically diverse CRISPR-Cas9 orthologs

por Giedrius Gasiunas, Joshua K. Young, Tautvydas Karvelis, Darius Kazlauskas, Tomas Urbaitis, Monika Jasnauskaite, Mantvyda M. Grusyte, Sushmitha Paulraj, Po-Hao Wang, Zhenglin Hou, Shane K. Dooley, Mark Cigan, Clara Alarcon, N. Doane Chilcoat, Greta Bigelyte, Jennifer L. Curcuru, Megumu Mabuchi, Zhiyi Sun, Ryan T. Fuchs, Ezra Schildkraut, Peter R. Weigele, William E. Jack, G. Brett Robb, Česlovas Venclovas, Virginijus Siksnys
Publicado 2020

miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC

por Young-Jun Jeon, Taewan Kim, Dongju Park, Gerard J. Nuovo, Siyeon Rhee, Pooja Joshi, Bum-Kyu Lee, Johan Jeong, Sung-suk Suh, Jeff E. Grotzke, Sung-Hak Kim, Jieun Song, Hosung Sim, Yonghwan Kim, Yong Peng, Youngtae Jeong, Michela Garofalo, Nicola Zanesi, Jonghwan Kim, Guang Liang, Ichiro Nakano, Peter Cresswell, Patrick Nana-Sinkam, Ri Cui, Carlo M. Croce
Publicado 2018

Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia

por Liping Dou, Fei Yan, Jiuxia Pang, Dehua Zheng, Dandan Li, Li Gao, Lijun Wang, Yihan Xu, Jinlong Shi, Qian Wang, Lei Zhou, Na Shen, Puja Singh, Lili Wang, Yonghui Li, Yvchi Gao, Tao Liu, Chongjian Chen, Aref Al-Kali, Mark R. Litzow, Young-In Chi, Ann M. Bode, Chunhui Liu, Haojie Huang, Daihong Liu, Guido Marcucci, Shujun Liu, Li Yu
Publicado 2019

Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours

por Lars Custers, Eleonora Khabirova, Tim H. H. Coorens, Thomas R. W. Oliver, Camilla Calandrini, Matthew D. Young, Felipe A. Vieira Braga, Peter Ellis, Lira Mamanova, Heidi Segers, Arie Maat, Marcel Kool, Eelco W. Hoving, Marry M. van den Heuvel-Eibrink, James Nicholson, Karin Straathof, Liz Hook, Ronald R. de Krijger, Claire Trayers, Kieren Allinson, Sam Behjati, Jarno Drost
Publicado 2021

Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

por Ji A Seo, Min-Cheol Kang, Won-Mo Yang, Won Min Hwang, Sang Soo Kim, Soo Hyun Hong, Jee-In Heo, Achana Vijyakumar, Leandro Pereira de Moura, Aykut Uner, Hu Huang, Seung Hwan Lee, Inês S. Lima, Kyong Soo Park, Min Seon Kim, Yossi Dagon, Thomas E. Willnow, Vanita Aroda, Theodore P. Ciaraldi, Robert R. Henry, Young-Bum Kim
Publicado 2020

Author Correction: Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

por Ji A. Seo, Min-Cheol Kang, Won-Mo Yang, Won Min Hwang, Sang Soo Kim, Soo Hyun Hong, Jee-In Heo, Achana Vijyakumar, Leandro Pereira de Moura, Aykut Uner, Hu Huang, Seung Hwan Lee, Inês S. Lima, Kyong Soo Park, Min Seon Kim, Yossi Dagon, Thomas E. Willnow, Vanita Aroda, Theodore P. Ciaraldi, Robert R. Henry, Young-Bum Kim
Publicado 2020

Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study

por Min Kyung Chu, Byung-Su Kim, Pil-Wook Chung, Byung-Kun Kim, Mi Ji Lee, Jeong Wook Park, Jin-Young Ahn, Dae Woong Bae, Tae-Jin Song, Jong-Hee Sohn, Kyungmi Oh, Daeyoung Kim, Jae-Moon Kim, Soo-Kyoung Kim, Yun-Ju Choi, Jae Myun Chung, Heui-Soo Moon, Chin-Sang Chung, Kwang-Yeol Park, Soo-Jin Cho
Publicado 2021

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

por Silvia Pomella, Prethish Sreenivas, Berkley E. Gryder, Long Wang, David Milewski, Matteo Cassandri, Kunal Baxi, Nicole R. Hensch, Elena Carcarino, Young Song, Hsien-Chao Chou, Marielle E. Yohe, Benjamin Z. Stanton, Bruno Amadio, Ignazio Caruana, Cristiano De Stefanis, Rita De Vito, Franco Locatelli, Yidong Chen, Eleanor Y. Chen, Peter Houghton, Javed Khan, Rossella Rota, Myron S. Ignatius
Publicado 2021

Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule

por Małgorzata A. Witek, Rachel D. Aufforth, Hong Wang, Joyce W. Kamande, Joshua M. Jackson, Swathi R. Pullagurla, Mateusz L. Hupert, Jerry Usary, Weiya Z. Wysham, Dawud Hilliard, Stephanie Montgomery, Victoria Bae-Jump, Lisa A. Carey, Paola A. Gehrig, Matthew I. Milowsky, Charles M. Perou, John T. Soper, Young E. Whang, Jen Jen Yeh, George Martin, Steven A. Soper
Publicado 2017

Alginate-Capped Silver Nanoparticles as a Potent Anti-mycobacterial Agent Against Mycobacterium tuberculosis

por Cheng-Cheung Chen, Cheng-Cheung Chen, Yih-Yuan Chen, Chang-Ching Yeh, Chia-Wei Hsu, Shang-Jie Yu, Chih-Hao Hsu, Ting-Chun Wei, Sin-Ni Ho, Pei-Chu Tsai, Yung-Deng Song, Hui-Ju Yen, Hui-Ju Yen, Xin-An Chen, Jenn-Jong Young, Chuan-Chung Chuang, Chuan-Chung Chuang, Horng-Yunn Dou, Horng-Yunn Dou
Publicado 2021

Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.

por Christopher S Carlson, Tara C Matise, Kari E North, Christopher A Haiman, Megan D Fesinmeyer, Steven Buyske, Fredrick R Schumacher, Ulrike Peters, Nora Franceschini, Marylyn D Ritchie, David J Duggan, Kylee L Spencer, Logan Dumitrescu, Charles B Eaton, Fridtjof Thomas, Alicia Young, Cara Carty, Gerardo Heiss, Loic Le Marchand, Dana C Crawford, Lucia A Hindorff, Charles L Kooperberg, PAGE Consortium
Publicado 2013

CD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE.

por Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord, Jim Young, Mina Psichogiou, Laurence Meyer, Sylvie Ayayi, Sophie Grabar, Francois Raffi, Peter Reiss, Brian Gazzard, Mike Sharland, Félix Gutierrez, Niels Obel, Ole Kirk, José M Miro, Hansjakob Furrer, Antonella Castagna, Stéphane De Wit, Josefa Muñoz, Jesper Kjaer, Jesper Grarup, Geneviève Chêne, Heiner Bucher
Publicado 2012

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

por Stephanie J. Alexopoulos, Sing-Young Chen, Amanda E. Brandon, Joseph M. Salamoun, Frances L. Byrne, Christopher J. Garcia, Martina Beretta, Ellen M. Olzomer, Divya P. Shah, Ashleigh M. Philp, Stefan R. Hargett, Robert T. Lawrence, Brendan Lee, James Sligar, Pascal Carrive, Simon P. Tucker, Andrew Philp, Carolin Lackner, Nigel Turner, Gregory J. Cooney, Webster L. Santos, Kyle L. Hoehn
Publicado 2020

Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

por Aleksander Skardal, Sean V. Murphy, Mahesh Devarasetty, Ivy Mead, Hyun-Wook Kang, Young-Joon Seol, Yu Shrike Zhang, Su-Ryon Shin, Liang Zhao, Julio Aleman, Adam R. Hall, Thomas D. Shupe, Andre Kleensang, Mehmet R. Dokmeci, Sang Jin Lee, John D. Jackson, James J. Yoo, Thomas Hartung, Ali Khademhosseini, Shay Soker, Colin E. Bishop, Anthony Atala
Publicado 2017

Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy

por Ameya R. Kirtane, Omar Abouzid, Daniel Minahan, Taylor Bensel, Alison L. Hill, Christian Selinger, Anna Bershteyn, Morgan Craig, Shirley S. Mo, Hormoz Mazdiyasni, Cody Cleveland, Jaimie Rogner, Young-Ah Lucy Lee, Lucas Booth, Farhad Javid, Sarah J. Wu, Tyler Grant, Andrew M. Bellinger, Boris Nikolic, Alison Hayward, Lowell Wood, Philip A. Eckhoff, Martin A. Nowak, Robert Langer, Giovanni Traverso
Publicado 2018