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  1. 2021
    mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion
    “... this is regulated is not clear. Here the authors show that mTORC1 signalling but not Xbp1-mediated transcription...”
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  2. 2022
    Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway
    “..., the authors show that aging related intestinal decline is mediated by activation of the mTORC1-p38MAPK-p53...”
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  3. 2023
    Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity
    “...Abstract Membrane potential controls the response of the M2 muscarinic receptor to its ligands...”
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  4. 2024
    Author Correction: Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein
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  5. 2025
    NADPH oxidase NOX4 is a glycolytic regulator through mROS-HIF1α axis in thyroid carcinomas
    “... its functional partner p22phox/CYBA. As a result, the increasement of mitochondrial ROS(m...”
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  6. 2026
    The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis
    “... of the Hippo signaling pathway, induces beta-cell failure through mTORC1 hyperactivation and autophagic flux...”
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  7. 2027
    In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
    “... CRISPR screen in TNBCs, the authors identify tumorigenic functions for components of the mTORC1/2 complex...”
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  8. 2028
    Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
    “...-quadruplex structure present within the EBNA1 mRNA....”
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  9. 2029
    NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation
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  10. 2030
    P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development
    “..., cells sense the fitness of their neighbours and trigger p53 to repress mTOR to eliminate a third...”
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  11. 2031
    Integrative Analysis of the Roles of lncRNAs and mRNAs in Itaconate-Mediated Protection Against Liver Ischemia-Reperfusion Injury in Mice
    por Xu Y, Li Z, Lu S, Wang C, Ke S, Li X, Yin B, Yu H, Zhou M, Pan S, Jiang H, Ma Y
    Publicado 2021
    “... analysis.Results: Itaconate attenuated liver IR injury. A total of 138 lncRNAs and 156 messenger RNAs (mRNAs) were...”
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  12. 2032
    Chemical profiling, in vitro antioxidant, membrane stabilizing and antimicrobial properties of wild growing Murraya paniculata from Amarkantak (M.P.)
    “... extract demonstrated considerable ABTS inhibitory activity (IC50value:555.18 ± 1.68 µg/mL) and the hexane...”
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  13. 2033
    In vivo imaging of mGlu5 receptor expression in humans with Fragile X Syndrome towards development of a potential biomarker
    “...) leads to excessive glutamate signaling via metabotropic glutamate subtype 5 receptors (mGluR5) which has...”
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  14. 2034
    I'm alone but not lonely. U-shaped pattern of self-perceived loneliness during the COVID-19 pandemic in the UK and Greece
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  15. 2035
    Ra'anan, Uri. <em>The U.S.S.R. Arms the Third World</em>, M.I.T. Press, Cambridge Massachusetts, 1969.
    por Carlos Rico Ferrat
    Publicado 1972
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  16. 2036
    Antiphospholipid Antibodies From Women With Pregnancy Morbidity and Vascular Thrombosis Induce Endothelial Mitochondrial Dysfunction, mTOR Activation, and Autophagy
    Materias: “...mTOR...”
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  17. 2037
    Development of Graves' Disease After SARS-CoV-2 mRNA Vaccination: A Case Report and Literature Review
    “... developed Graves' disease after BNT162b2 mRNA vaccine. A search of PubMed and Embase databases from 1...”
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  18. 2038
    Micellar emulsions composed of mPEG-PCL/MCT as novel nanocarriers for systemic delivery of genistein: a comparative study with micelles
    por Zhang TP, Wang H, Ye YH, Zhang XW, Wu BJ
    Publicado 2015
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  19. 2039
    Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity
    por Duan YR, Liu PF, Qiu M, Li Q, Yin PH, Wang Y, Qiu YY, Hou LL, Liu X, Qin JM
    Publicado 2012
    “... efficacy of nanoparticles (NPs) made of methoxy polyethylene glycol (mPEG), polylactic-co-glycolic acid...”
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  20. 2040
    Altered NCF2, NOX2 mRNA Expression Levels in Peripheral Blood Mononuclear Cells of Pulmonary Tuberculosis Patients
    por Li HM, Huang Q, Tang F, Zhang TP
    Publicado 2021
    “... to invading microorganisms including M. tuberculosis (MTB). NCF2 and NOX2 were considered as important...”
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