Mostrando 141 - 160 Resultados de 899 Para Buscar '"p53"', tiempo de consulta: 0.32s Limitar resultados
  1. 141
    Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours
    “...Several breast cancers may originate from mammary luminal cells and inactivating mutations of p53...”
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  2. 142
    A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours
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  3. 143
    Activation of wild-type p53 by MDM2 inhibitors: a new strategy for lymphoma treatment
    por Pujals A, Favre L, Gaulard P, Wiels J
    Publicado 2015
    “...2. In the past 10 years, major efforts have been made to develop drugs that can reactivate p53...”
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  4. 144
    Investigation of solvent effect and NMR shielding tensors of p53 tumor-suppressor gene in drug design
    por S Irani, M Monajjemi, B Honarparvar, et al
    Publicado 2011
    “..., Tehran, IranAbstract: The p53 tumor-suppressor gene encodes a nuclear phosphoprotein with cancer...”
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  5. 145
    Decitabine activates type I interferon signaling to inhibit p53‐deficient myeloid malignant cells
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  6. 146
    PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth
    “...Acetylation of p53 is critical for its transcriptional activity and its tumour suppressive function...”
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  7. 147
    Phenotype of p53 wild-type epitope-specific T cells in the circulation of patients with head and neck cancer
    “...Abstract CD8+ cytotoxic T-cell (CTL) specific for non-mutated, wild type (wt) sequence p53 peptides...”
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  8. 148
    Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246
    “...Abstract The tumor suppressor p53 is commonly inactivated in human tumors, allowing evasion of p53...”
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  9. 149
    Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation
    “...Abstract The prevalence and dire implications of mutations in the tumour suppressor, p53, highlight...”
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  10. 150
    Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation
    “... identify redistribution of p53 and CTCF genomic binding to be associated with transcriptional...”
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  11. 151
    Cisatracurium besilate enhances the TRAIL-induced apoptosis of gastric cancer cells via p53 signaling
    por Qiang Zhou, Jianxia Yuan, Yi Liu, Yayun Wu
    Publicado 2021
    “..., respectively. Furthermore, the expression levels of p53 and p53 upregulated modulator of apoptosis (PUMA) were...”
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  12. 152
    Oligomerization of Mutant p53 R273H is not Required for Gain-of-Function Chromatin Associated Activities
    Materias: “...mutant p53...”
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  13. 153
    Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.
    “... as a novel downstream target of the p53 tumor suppressor protein. Bioinformatic analysis of the SALL2...”
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  14. 154
    p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner.
    “...<h4>Background</h4>The tumor suppressor p53 is an important regulator that controls various...”
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  15. 155
    Assessment of changes in the brca2 and p53 genes in breast invasive ductal carcinoma in northeast Brazil
    “... in preclinical models. RESULTS: BRCA2 methylation frequency was 44%, p53 Pro22 allele frequency was 32...”
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  16. 156
    Sera Anti-P53 Antibody Provides New Information Which Explains the Link Between Diabetes and Cancer
    Materias: “...anti-p53 antibodies...”
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  17. 157
    Immunoexpression of p53 in Oral Squamous Cell Carcinoma and Oral Dysplastic Lesions in Patients with the Habit of Reverse Smoke
    Materias: “...p53...”
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  18. 158
    Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
    “...p53 gain of function mutants (mutp53) are involved in the pathogenesis of most human cancers. Here...”
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  19. 159
    Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates
    “...The tumor suppressor p53 is a master regulator of cellular stress response pathways, including cell...”
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  20. 160
    Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity
    “... to directly demonstrate that p53 acetylation modulates promoter residence time and transcriptional activity....”
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