Mostrando 1 - 20 Resultados de 899 Para Buscar '"p53"', tiempo de consulta: 0.15s Limitar resultados
  1. 1
    Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation
    “...Codon 158 gain-of-function mutant p53 (158-mutp53) promotes tumourigenesis in lung cancer. Here...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  2. 2
    The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation.
    “...The naturally occurring Δ40p53 isoform heterotetramerizes with wild-type p53 (WTp53) to regulate...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  3. 3
    p53 e as hemopatias malignas
    Materias: “...Gene p53...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  4. 4
    EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction
    “... to show a direct interaction between EGCG and the tumor suppressor p53 and demonstrate that EGCG inhibits...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  5. 5
    Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
    “...Most mutant p53 heterozygous tumours undergo loss of the remaining wildtype (WT) p53 allele which...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  6. 6
    A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
    por Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
    Publicado 2018
    “...Activation of the tumor suppressor p53 is a promising approach in cancer therapy. Here, the authors...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  7. 7
    Inhibition of p53-dependent, but not p53-independent, cell death by U19 protein from human herpesvirus 6B.
    “... suppressor protein p53. In this study, we have analyzed the activity of p53 after stimulation with p53...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  8. 8
    Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines.
    “...The carboxy-terminal truncated p53 alternative spliced isoforms, p53β and p53γ, are expressed...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  9. 9
    Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
    por Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
    Publicado 2018
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  10. 10
    Loss of wild-type p53 promotes mutant p53-driven metastasis through acquisition of survival and tumor-initiating properties
    “...Both gain-of-function of mutant p53 (GOF) and loss of wild-type p53 (LOH) are independently...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  11. 11
    Polimorfismos de p53 y enfermedad coronaria
    por Verdejo,Hugo
    Publicado 2009
    Enlace del recurso
    Agregar a favoritos
    Guardado en:
  12. 12
    Novel p53 therapies for head and neck cancer
    por Mario R. Castellanos, Quintin Pan
    Publicado 2016
    “...Inactivation of the tumor suppressor p53 is the predominant pathogenetic event in head and neck...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  13. 13
    Structure of the p53/RNA polymerase II assembly
    “...Liou et al. report a 4.6 Å resolution structure of the human p53/ RNA polymerase II assembly, using...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  14. 14
    Developmental Acquisition of <i>p53</i> Functions
    “...Remarkably, the <i>p53</i> transcription factor, referred to as “the guardian of the genome...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  15. 15
    The Basally Expressed p53-Mediated Homeostatic Function
    por Isha Nagpal, Zhi-Min Yuan
    Publicado 2021
    Materias: “...basal p53...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  16. 16
    KI67 AND P53 PROTEINS IN ODONTOGENIC KERATOCYST
    Materias: “...p53 protein...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  17. 17
    PEPD is a pivotal regulator of p53 tumor suppressor
    “...p53 is a pivotal tumour suppressor that is activated by various cellular stress inducers. Here...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  18. 18
    p53 downregulates the Fanconi anaemia DNA repair pathway
    “...P53 is regarded as the guardian of the genome, however it is known that mice with increased p53...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  19. 19
    Complexes formed by mutant p53 and their roles in breast cancer
    Materias: “...mutant p53 gain-of-function...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  20. 20
    The p53 breast cancer tissue biomarker in Indian women
    “... chemotherapy is highly effective in locally advanced breast cancer. A negative expression of biomarker p53...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
Herramientas de búsqueda: RSS — Enviar por Correo electrónico esta Búsqueda — Guardar Búsqueda