Machine learning can identify newly diagnosed patients with CLL at high risk of infection

por Rudi Agius, Christian Brieghel, Michael A. Andersen, Alexander T. Pearson, Bruno Ledergerber, Alessandro Cozzi-Lepri, Yoram Louzoun, Christen L. Andersen, Jacob Bergstedt, Jakob H. von Stemann, Mette Jørgensen, Man-Hung Eric Tang, Magnus Fontes, Jasmin Bahlo, Carmen D. Herling, Michael Hallek, Jens Lundgren, Cameron Ross MacPherson, Jan Larsen, Carsten U. Niemann
Publicado 2020

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

por Jian Xu, Manavi Chatterjee, Tyler D Baguley, Jonathan Brouillette, Pradeep Kurup, Debolina Ghosh, Jean Kanyo, Yang Zhang, Kathleen Seyb, Chimezie Ononenyi, Ethan Foscue, George M Anderson, Jodi Gresack, Gregory D Cuny, Marcie A Glicksman, Paul Greengard, TuKiet T Lam, Lutz Tautz, Angus C Nairn, Jonathan A Ellman, Paul J Lombroso
Publicado 2014

High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy

por Chialin Cheng, Surya A. Reis, Emily T. Adams, Daniel M. Fass, Steven P. Angus, Timothy J. Stuhlmiller, Jared Richardson, Hailey Olafson, Eric T. Wang, Debasis Patnaik, Roberta L. Beauchamp, Danielle A. Feldman, M. Catarina Silva, Mriganka Sur, Gary L. Johnson, Vijaya Ramesh, Bruce L. Miller, Sally Temple, Kenneth S. Kosik, Bradford C. Dickerson, Stephen J. Haggarty
Publicado 2021

Atomistic characterization of the active-site solvation dynamics of a model photocatalyst

por Tim B. van Driel, Kasper S. Kjær, Robert W. Hartsock, Asmus O. Dohn, Tobias Harlang, Matthieu Chollet, Morten Christensen, Wojciech Gawelda, Niels E. Henriksen, Jong Goo Kim, Kristoffer Haldrup, Kyung Hwan Kim, Hyotcherl Ihee, Jeongho Kim, Henrik Lemke, Zheng Sun, Villy Sundström, Wenkai Zhang, Diling Zhu, Klaus B. Møller, Martin M. Nielsen, Kelly J. Gaffney
Publicado 2016

Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery

por Andrew R. Burns, Genna M. Luciani, Gabriel Musso, Rachel Bagg, May Yeo, Yuqian Zhang, Luckshi Rajendran, John Glavin, Robert Hunter, Elizabeth Redman, Susan Stasiuk, Michael Schertzberg, G. Angus McQuibban, Conor R. Caffrey, Sean R. Cutler, Mike Tyers, Guri Giaever, Corey Nislow, Andy G. Fraser, Calum A. MacRae, John Gilleard, Peter J. Roy
Publicado 2020

A meta-analysis of the relationship between FGFR3 and TP53 mutations in bladder cancer.

por Yann Neuzillet, Xavier Paoletti, Slah Ouerhani, Pierre Mongiat-Artus, Hany Soliman, Hugues de The, Mathilde Sibony, Yves Denoux, Vincent Molinie, Aurélie Herault, May-Linda Lepage, Pascale Maille, Audrey Renou, Dimitri Vordos, Claude-Clément Abbou, Ashraf Bakkar, Bernard Asselain, Nadia Kourda, Amel El Gaaied, Karen Leroy, Agnès Laplanche, Simone Benhamou, Thierry Lebret, Yves Allory, François Radvanyi
Publicado 2012

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

por Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Wardak, Lung-Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessene, John Silke, Peter E. Czabotar, Andrew I. Webb, James M. Murphy
Publicado 2018

Earliest Olduvai hominins exploited unstable environments ~ 2 million years ago

por Julio Mercader, Pam Akuku, Nicole Boivin, Revocatus Bugumba, Pastory Bushozi, Alfredo Camacho, Tristan Carter, Siobhán Clarke, Arturo Cueva-Temprana, Paul Durkin, Julien Favreau, Kelvin Fella, Simon Haberle, Stephen Hubbard, Jamie Inwood, Makarius Itambu, Samson Koromo, Patrick Lee, Abdallah Mohammed, Aloyce Mwambwiga, Lucas Olesilau, Robert Patalano, Patrick Roberts, Susan Rule, Palmira Saladie, Gunnar Siljedal, María Soto, Jonathan Umbsaar, Michael Petraglia
Publicado 2021

c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae

por Kyle A. Floyd, Calvin K. Lee, Wujing Xian, Mahmoud Nametalla, Aneesa Valentine, Benjamin Crair, Shiwei Zhu, Hannah Q. Hughes, Jennifer L. Chlebek, Daniel C. Wu, Jin Hwan Park, Ali M. Farhat, Charles J. Lomba, Courtney K. Ellison, Yves V. Brun, Javier Campos-Gomez, Ankur B. Dalia, Jun Liu, Nicolas Biais, Gerard C. L. Wong, Fitnat H. Yildiz
Publicado 2020

Cocculus hirsutus-Derived Phytopharmaceutical Drug Has Potent Anti-dengue Activity

por Rahul Shukla, Ravi Kant Rajpoot, Ankur Poddar, Richa Ahuja, Hemalatha Beesetti, Rajgokul K. Shanmugam, Shivam Chaturvedi, Kaushal Nayyar, Deepika Singh, Venugopal Singamaneni, Prasoon Gupta, Ajai Prakash Gupta, Sumeet Gairola, Pankaj Kumar, Y. S. Bedi, Tapesh Jain, Bhupendra Vashishta, Ravindra Patil, Harish Madan, Sumit Madan, Rinku Kalra, Ruchi Sood, Ram A. Vishwakarma, D. Srinivasa Reddy, Altaf A. Lal, Upasana Arora, Navin Khanna
Publicado 2021

The challenge of conserving amphibian megadiversity in Madagascar.

por Franco Andreone, Angus I Carpenter, Neil Cox, Louis du Preez, Karen Freeman, Samuel Furrer, Gerardo Garcia, Frank Glaw, Julian Glos, David Knox, Jörn Köhler, Joseph R Mendelson, Vincenzo Mercurio, Russell A Mittermeier, Robin D Moore, Nirhy H C Rabibisoa, Herilala Randriamahazo, Harison Randrianasolo, Noromalala Rasoamampionona Raminosoa, Olga Ravoahangimalala Ramilijaona, Christopher J Raxworthy, Denis Vallan, Miguel Vences, David R Vieites, Ché Weldon
Publicado 2008

Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection

por Rachel Wheatley, Julio Diaz Caballero, Natalia Kapel, Fien H. R. de Winter, Pramod Jangir, Angus Quinn, Ester del Barrio-Tofiño, Carla López-Causapé, Jessica Hedge, Gabriel Torrens, Thomas Van der Schalk, Basil Britto Xavier, Felipe Fernández-Cuenca, Angel Arenzana, Claudia Recanatini, Leen Timbermont, Frangiscos Sifakis, Alexey Ruzin, Omar Ali, Christine Lammens, Herman Goossens, Jan Kluytmans, Samir Kumar-Singh, Antonio Oliver, Surbhi Malhotra-Kumar, Craig MacLean
Publicado 2021

Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

por Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, Xue-Lin Kwang, Fui-Teen Chong, Ankur Sharma, Denis Bertrand, Shen Yon Toh, Hui-Sun Leong, Matan T. Thangavelu, Jacqueline S. G. Hwang, Kok-Hing Lim, Thakshayeni Skanthakumar, Hiang-Khoon Tan, Yan Su, Siang Hui Choo, Hannes Hentze, Iain B. H. Tan, Alexander Lezhava, Patrick Tan, Daniel S. W. Tan, Giridharan Periyasamy, Judice L. Y. Koh, N. Gopalakrishna Iyer, Ramanuj DasGupta
Publicado 2017

Asian Pacific Society of Cardiology Consensus Recommendations on the Use of MitraClip for Mitral Regurgitation

por Khung Keong Yeo, Jack Wei Chieh Tan, David WM Muller, Darren L Walters, JoAnn Lindenfeld, Michael Kang Yin Lee, Angus Shing Fung Chui, Sai Satish, Teguh Santoso, Shunsuke Kubo, John Chan Kok Meng, Kenny YK Sin, See Hooi Ewe, David Sim, Edgar Tay, Krissada Meemook, Shih-Hsien Sung, Quang Ngoc Nguyen, Xiangbin Pan, Makoto Amaki, Masaki Izumo, Kentaro Hayashida, Jung Sun Kim, Do-Yoon Kang, Gregg Stone, Takashi Matsumoto
Publicado 2021

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity

por Jacqueline H. L. Fok, Antonio Ramos-Montoya, Mercedes Vazquez-Chantada, Paul W. G. Wijnhoven, Valeria Follia, Neil James, Paul M. Farrington, Ankur Karmokar, Sophie E. Willis, Jonathan Cairns, Jenni Nikkilä, David Beattie, Gillian M. Lamont, M. Raymond V. Finlay, Joanne Wilson, Aaron Smith, Lenka Oplustil O’Connor, Stephanie Ling, Stephen E. Fawell, Mark J. O’Connor, Simon J. Hollingsworth, Emma Dean, Frederick W. Goldberg, Barry R. Davies, Elaine B. Cadogan
Publicado 2019