Cellular 3D-reconstruction and analysis in the human cerebral cortex using automatic serial sections

por Nick Y. Larsen, Xixia Li, Xueke Tan, Gang Ji, Jing Lin, Grazyna Rajkowska, Jesper Møller, Ninna Vihrs, Jon Sporring, Fei Sun, Jens R. Nyengaard
Publicado 2021

Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice

por Maud Voisin, Elina Shrestha, Claire Rollet, Cyrus A. Nikain, Tatjana Josefs, Mélanie Mahé, Tessa J. Barrett, Hye Rim Chang, Rachel Ruoff, Jeffrey A. Schneider, Michela L. Garabedian, Chris Zoumadakis, Chi Yun, Bara Badwan, Emily J. Brown, Adam C. Mar, Robert J. Schneider, Ira J. Goldberg, Inés Pineda-Torra, Edward A. Fisher, Michael J. Garabedian
Publicado 2021

Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer

por Wei Guo, Yuchao Zhang, Shiwei Guo, Zi Mei, Huiping Liao, Hang Dong, Kai Wu, Haocheng Ye, Yuhang Zhang, Yufei Zhu, Jingyu Lang, Landian Hu, Gang Jin, Xiangyin Kong
Publicado 2021

CENP-A overexpression promotes distinct fates in human cells, depending on p53 status

por Daniel Jeffery, Alberto Gatto, Katrina Podsypanina, Charlène Renaud-Pageot, Rebeca Ponce Landete, Lorraine Bonneville, Marie Dumont, Daniele Fachinetti, Geneviève Almouzni
Publicado 2021

Imaging the electrical activity of organelles in living cells

por Ella Matamala, Cristian Castillo, Juan P. Vivar, Patricio A. Rojas, Sebastian E. Brauchi
Publicado 2021

Damage-free light-induced assembly of intestinal bacteria with a bubble-mimetic substrate

por Kota Hayashi, Yasuyuki Yamamoto, Mamoru Tamura, Shiho Tokonami, Takuya Iida
Publicado 2021

High-resolution cryo-EM structure of photosystem II reveals damage from high-dose electron beams

por Koji Kato, Naoyuki Miyazaki, Tasuku Hamaguchi, Yoshiki Nakajima, Fusamichi Akita, Koji Yonekura, Jian-Ren Shen
Publicado 2021

Building a Chinese pan-genome of 486 individuals

por Qiuhui Li, Shilin Tian, Bin Yan, Chi Man Liu, Tak-Wah Lam, Ruiqiang Li, Ruibang Luo
Publicado 2021

ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity

por Maria Giovanna Garone, Nicol Birsa, Maria Rosito, Federico Salaris, Michela Mochi, Valeria de Turris, Remya R. Nair, Thomas J. Cunningham, Elizabeth M. C. Fisher, Mariangela Morlando, Pietro Fratta, Alessandro Rosa
Publicado 2021

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

por Louise van der Weyden, Victoria Harle, Gemma Turner, Victoria Offord, Vivek Iyer, Alastair Droop, Agnieszka Swiatkowska, Roy Rabbie, Andrew D. Campbell, Owen J. Sansom, Mercedes Pardo, Jyoti S. Choudhary, Ingrid Ferreira, Mark Tullett, Mark J. Arends, Anneliese O. Speak, David J. Adams
Publicado 2021

A high-resolution real-time quantification of astrocyte cytokine secretion under shear stress for investigating hydrocephalus shunt failure

por Fatemeh Khodadadei, Allen P. Liu, Carolyn A. Harris
Publicado 2021

Bacteria-specific pro-photosensitizer kills multidrug-resistant Staphylococcus aureus and Pseudomonas aeruginosa

por Min Lu, Yongli Li, Mei X. Wu
Publicado 2021

Teasing apart the cell death pathways in HIV pathogenesis

por Karli Montague-Cardoso
Publicado 2021

Targeting the undruggable: an interview with Leila Akkari on fighting cancer by rewiring cells

Publicado 2021

Worker ants promote outbreeding by transporting young queens to alien nests

por Mathilde Vidal, Florian Königseder, Julia Giehr, Alexandra Schrempf, Christophe Lucas, Jürgen Heinze
Publicado 2021

Plant single-cell solutions for energy and the environment

por Benjamin Cole, Dominique Bergmann, Crysten E. Blaby-Haas, Ian K. Blaby, Kristofer E. Bouchard, Siobhan M. Brady, Doina Ciobanu, Devin Coleman-Derr, Samuel Leiboff, Jenny C. Mortimer, Tatsuya Nobori, Seung Y. Rhee, Jeremy Schmutz, Blake A. Simmons, Anup K. Singh, Neelima Sinha, John P. Vogel, Ronan C. O’Malley, Axel Visel, Diane E. Dickel
Publicado 2021

Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration

por Manuel J. Carrasco, Suman Alishetty, Mohamad-Gabriel Alameh, Hooda Said, Lacey Wright, Mikell Paige, Ousamah Soliman, Drew Weissman, Thomas E. Cleveland, Alexander Grishaev, Michael D. Buschmann
Publicado 2021

ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance

por Su Chul Jang, Kyriakos D. Economides, Raymond J. Moniz, Chang Ling Sia, Nuruddeen Lewis, Christine McCoy, Tong Zi, Kelvin Zhang, Rane A. Harrison, Joanne Lim, Joyoti Dey, Marc Grenley, Katherine Kirwin, Nikki L. Ross, Raymond Bourdeau, Agata Villiger-Oberbek, Scott Estes, Ke Xu, Jorge Sanchez-Salazar, Kevin Dooley, William K. Dahlberg, Douglas E. Williams, Sriram Sathyanarayanan
Publicado 2021

Lepidopteran wing scales contain abundant cross-linked film-forming histidine-rich cuticular proteins

por Jianqiu Liu, Zhiwei Chen, Yingdan Xiao, Tsunaki Asano, Shenglong Li, Li Peng, Enxiang Chen, Jiwei Zhang, Wanshun Li, Yan Zhang, Xiaoling Tong, Keiko Kadono-Okuda, Ping Zhao, Ningjia He, Kallare P. Arunkumar, Karumathil P. Gopinathan, Qingyou Xia, Judith H. Willis, Marian R. Goldsmith, Kazuei Mita
Publicado 2021

Genomic divergence during feralization reveals both conserved and distinct mechanisms of parallel weediness evolution

por Toshiyuki Imaizumi, Kaworu Ebana, Yoshihiro Kawahara, Chiaki Muto, Hiroyuki Kobayashi, Akira Koarai, Kenneth M. Olsen
Publicado 2021