Vitamin D upregulates the macrophage complement receptor immunoglobulin in innate immunity to microbial pathogens

por Annabelle G. Small, Sarah Harvey, Jaspreet Kaur, Trishni Putty, Alex Quach, Usma Munawara, Khalida Perveen, Andrew McPhee, Charles S. Hii, Antonio Ferrante
Publicado 2021

Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS

por Han-Xiang Deng, Hong Zhai, Yong Shi, Guoxiang Liu, Jessica Lowry, Bin Liu, Éanna B. Ryan, Jianhua Yan, Yi Yang, Nigel Zhang, Zhihua Yang, Erdong Liu, Yongchao C. Ma, Teepu Siddique
Publicado 2021

Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

por Lesley Cheng, Camelia Quek, Xia Li, Shayne A. Bellingham, Laura J. Ellett, Mitch Shambrook, Saima Zafar, Inga Zerr, Victoria A. Lawson, Andrew F. Hill
Publicado 2021

Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice

por José Gabriel Barcia Durán, Tyler Lu, Sean Houghton, Fuqiang Geng, Ryan Schreiner, Jenny Xiang, Shahin Rafii, David Redmond, Raphaël Lis
Publicado 2021

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis

por Ryan S. Dhindsa, Johan Mattsson, Abhishek Nag, Quanli Wang, Louise V. Wain, Richard Allen, Eleanor M. Wigmore, Kristina Ibanez, Dimitrios Vitsios, Sri V. V. Deevi, Sebastian Wasilewski, Maria Karlsson, Glenda Lassi, Henric Olsson, Daniel Muthas, Susan Monkley, Alex Mackay, Lynne Murray, Simon Young, Carolina Haefliger, FinnGen Consortium, Toby M. Maher, Maria G. Belvisi, Gisli Jenkins, Philip L. Molyneaux, Adam Platt, Slavé Petrovski
Publicado 2021

A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells

por Yosi Gilad, Yossi Eliaz, Yang Yu, Adam M. Dean, San Jung Han, Li Qin, Bert W. O’Malley, David M. Lonard
Publicado 2021

Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome

por So-mi Kang, Min-Ho Yoon, Jinsook Ahn, Ji-Eun Kim, So Young Kim, Seock Yong Kang, Jeongmin Joo, Soyoung Park, Jung-Hyun Cho, Tae-Gyun Woo, Ah-Young Oh, Kyu Jin Chung, So Yon An, Tae Sung Hwang, Soo Yong Lee, Jeong-Su Kim, Nam-Chul Ha, Gyu-Yong Song, Bum-Joon Park
Publicado 2021

Environmental drivers of body size evolution in crocodile-line archosaurs

por Maximilian T. Stockdale, Michael J. Benton
Publicado 2021

Vitamin B6 deficiency disrupts serotonin signaling in pancreatic islets and induces gestational diabetes in mice

por Ashley M. Fields, Kevin Welle, Elaine S. Ho, Clementina Mesaros, Martha Susiarjo
Publicado 2021

Development of deep learning algorithms for predicting blastocyst formation and quality by time-lapse monitoring

por Qiuyue Liao, Qi Zhang, Xue Feng, Haibo Huang, Haohao Xu, Baoyuan Tian, Jihao Liu, Qihui Yu, Na Guo, Qun Liu, Bo Huang, Ding Ma, Jihui Ai, Shugong Xu, Kezhen Li
Publicado 2021

Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells

por Selva Rupa Christinal Immanuel, Avinash D. Ghanate, Dharmeshkumar S. Parmar, Ritu Yadav, Riya Uthup, Venkateswarlu Panchagnula, Anu Raghunathan
Publicado 2021

Pseudosparse neural coding in the visual system of primates

por Sidney R. Lehky, Keiji Tanaka, Anne B. Sereno
Publicado 2021

MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura

por Cheng-Kang Tang, Chih-Hsuan Tsai, Carol-P. Wu, Yu-Hsien Lin, Sung-Chan Wei, Yun-Heng Lu, Cheng-Hsun Li, Yueh-Lung Wu
Publicado 2021

DeepSleep convolutional neural network allows accurate and fast detection of sleep arousal

por Hongyang Li, Yuanfang Guan
Publicado 2021

Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors

por Tomohiko Matsuo, Tomoko Isosaka, Lijun Tang, Tomoyoshi Soga, Reiko Kobayakawa, Ko Kobayakawa
Publicado 2021

Author Correction: VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells

por Manon Penco-Campillo, Yannick Comoglio, Álvaro Javier Feliz Morel, Rita Hanna, Jérôme Durivault, Magalie Leloire, Bastien Mejias, Marina Pagnuzzi, Amandine Morot, Fanny Burel-Vandenbos, Matthew Selby, Daniel Williamson, Steven C. Clifford, Audrey Claren, Jérôme Doyen, Vincent Picco, Sonia Martial, Gilles Pagès
Publicado 2020

Structural basis of Naa20 activity towards a canonical NatB substrate

por Dominik Layer, Jürgen Kopp, Miriam Fontanillo, Maja Köhn, Karine Lapouge, Irmgard Sinning
Publicado 2021

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

por Thibault Viennet, Michael M. Wördehoff, Boran Uluca, Chetan Poojari, Hamed Shaykhalishahi, Dieter Willbold, Birgit Strodel, Henrike Heise, Alexander K. Buell, Wolfgang Hoyer, Manuel Etzkorn
Publicado 2018

Turnip mosaic virus in oilseed rape activates networks of sRNA-mediated interactions between viral and host genomes

por Nicolas Pitzalis, Khalid Amari, Stéfanie Graindorge, David Pflieger, Livia Donaire, Michael Wassenegger, César Llave, Manfred Heinlein
Publicado 2020

Author Correction: Transcriptomic immaturity inducible by neural hyperexcitation is shared by multiple neuropsychiatric disorders

por Tomoyuki Murano, Hideo Hagihara, Katsunori Tajinda, Mitsuyuki Matsumoto, Tsuyoshi Miyakawa
Publicado 2019