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  1. 1261
    A computational model of the LGI1 protein suggests a common binding site for ADAM proteins.
    “... was also used to predict effects of known disease-causing missense mutations. Most of the variants...”
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  2. 1262
    The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila.
    por Laura B Duvall, Paul H Taghert
    Publicado 2012
    “... pathways of circadian synchronization are mediated by highly specific second messenger components...”
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  3. 1263
    Essential role of the zinc transporter ZIP9/SLC39A9 in regulating the activations of Akt and Erk in B-cell receptor signaling pathway in DT40 cells.
    “... as a nutritional factor, but also as a second messenger. However, the effects of intracellular zinc...”
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  4. 1264
    Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses
    “... second messenger cGAMP that activates stimulator of interferon genes (STING) in infected cells...”
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  5. 1265
    Structural studies of the periplasmic portion of the diguanylate cyclase CdgH from Vibrio cholerae
    “...Abstract Cyclic diguanylate monophosphate (c-di-GMP) is a second messenger involved in bacterial...”
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  6. 1266
    Mutation Spectrum in the CACNA1A Gene in 49 Patients with Episodic Ataxia
    “... (three nonsense and three missense changes) and two coding indels, one of them found in two unrelated...”
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  7. 1267
    Structural insights into the RNA methyltransferase domain of METTL16
    “...Abstract N 6-methyladenosine (m6A) is an abundant modification in messenger RNA and noncoding RNAs...”
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  8. 1268
    The umami receptor T1R1–T1R3 heterodimer is rarely formed in chickens
    “... the possibility that there is another second messenger signaling system in chicken taste sensory cells. We also...”
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  9. 1269
    Mutational screening of SLC39A5, LEPREL1 and LRPAP1 in a cohort of 187 high myopia patients
    “... them, three novel missense mutations, c.860C > T, p.Pro287Leu and c.956G > C, p.Arg319Thr in SLC39A5, c...”
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  10. 1270
    Hotspot Mutations in SARS-CoV-2
    “... are discussed as well. Also, for all the non-synonymous substitutions (missense mutations), the functional...”
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  11. 1271
    Novel IL-12Rβ1 deficiency-mediates recurrent cutaneous leishmaniasis
    “... was identified, which was caused by a novel homozygous missense mutation (c.485>T/p.P162L) and a novel homozygous...”
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  12. 1272
    Identification of the circRNA-miRNA-mRNA Regulatory Network in Bladder Cancer by Bioinformatics Analysis
    “.... We obtained four datasets of circRNA, microRNA (miRNA), and messenger (mRNA) expression profiles from...”
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  13. 1273
    Effect of Elevated Ketone Body on Maternal and Infant Outcome of Pregnant Women with Abnormal Glucose Metabolism During Pregnancy
    por Qian M, Wu N, Li L, Yu W, Ouyang H, Liu X, He Y, Al-Mureish A
    Publicado 2020
    “...Meichen Qian,1 Na Wu,1,2 Ling Li,1 Wenshu Yu,1 Hong Ouyang,1 Xinyan Liu,1 Yujing He,1 Abdulrahman...”
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  14. 1274
    Rapid detection of phenotypes Bombay se del and nonsecretor rs200157007 SNP (302C > T) by real-time PCR-based methods
    por Mikiko Soejima, Yoshiro Koda
    Publicado 2021
    “... missense single nucleotide polymorphism (SNP), 302C > T, is characteristic of South Asians with a frequency...”
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  15. 1275
    Prioritizing variants of uncertain significance for reclassification using a rule-based algorithm in inherited retinal dystrophies
    “... and found there is a significant proof of deleteriousness when all score for pathogenicity in missense...”
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  16. 1276
    Current Status of Functional Studies on Circular RNAs in Rheumatoid Arthritis and Their Potential Role as Diagnostic Biomarkers
    por Xu Y, Chen F
    Publicado 2021
    “... University, 81 Meishan Road, Hefei, 230032, People’s Republic of ChinaEmail chenfeihu...”
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  17. 1277
    Exposure to PM2.5 during pregnancy causes lung inflammation in the offspring: Mechanism of action of mogrosides
    “... medicinally, where they can moisten the lungs and relieve coughing. In this study, pregnant rats were exposed...”
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  18. 1278
    Vibrio fischeri and Escherichia coli adhesion tendencies towards photolithographically modified nanosmooth poly (tert-butyl methacrylate) polymer surfaces
    “... Riessen3, Russell J Crawford11Faculty Life and Social Sciences; 2IRIS, Swinburne University of Technology...”
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  19. 1279
    Two novel ectodysplasin A gene mutations and prenatal diagnosis of X‐linked hypohidrotic ectodermal dysplasia
    “..., and the transcriptional NF‐κB activation induced by these missense mutant‐type EDA1 proteins was significantly reduced...”
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  20. 1280
    Improving body image at scale among Brazilian adolescents: study protocol for the co-creation and randomised trial evaluation of a chatbot intervention
    “... with the chatbot over a 72-hour period on Facebook Messenger. Primary outcomes will assess the immediate and short...”
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