A model for studying the hemostatic consumption or destruction of platelets.

por Mark R Dowling, Emma C Josefsson, Katya J Henley, Benjamin T Kile, Philip D Hodgkin
Publicado 2013

CHD7 deficiency in "Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairment.

por Jacqueline M Ogier, Marina R Carpinelli, Benedicta D Arhatari, R C Andrew Symons, Benjamin T Kile, Rachel A Burt
Publicado 2014

MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication.

por Peter Fleming, Marc Kvansakul, Valentina Voigt, Benjamin T Kile, Ruth M Kluck, David C S Huang, Mariapia A Degli-Esposti, Christopher E Andoniou
Publicado 2013

MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke.

por Catherine E Downes, Connie H Y Wong, Katya J Henley, Pedro L Guio-Aguilar, Moses Zhang, Robert Ates, Ashley Mansell, Benjamin T Kile, Peter J Crack
Publicado 2013

Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection.

por Lukasz Kedzierski, Edmond M Linossi, Tatiana B Kolesnik, E Bridie Day, Nicola L Bird, Benjamin T Kile, Gabrielle T Belz, Donald Metcalf, Nicos A Nicola, Katherine Kedzierska, Sandra E Nicholson
Publicado 2014

Acute myeloid leukemia maturation lineage influences residual disease and relapse following differentiation therapy

por Steven Ngo, Ethan P. Oxley, Margherita Ghisi, Maximilian M. Garwood, Mark D. McKenzie, Helen L. Mitchell, Peter Kanellakis, Olivia Susanto, Michael J. Hickey, Andrew C. Perkins, Benjamin T. Kile, Ross A. Dickins
Publicado 2021

Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses

por Geneviève Pépin, Dominic De Nardo, Christina L. Rootes, Tomalika R. Ullah, Sumaiah S. Al-Asmari, Katherine R. Balka, Hong-Mei Li, Kylie M. Quinn, Fiona Moghaddas, Stephane Chappaz, Benjamin T. Kile, Eric F. Morand, Seth L. Masters, Cameron R. Stewart, Bryan R. G. Williams, Michael P. Gantier
Publicado 2020

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

por Hazel Tye, Chien-Hsiung Yu, Lisa A. Simms, Marcel R. de Zoete, Man Lyang Kim, Martha Zakrzewski, Jocelyn S. Penington, Cassandra R. Harapas, Fernando Souza-Fonseca-Guimaraes, Leesa F. Wockner, Adele Preaudet, Lisa A. Mielke, Stephen A. Wilcox, Yasunori Ogura, Sinead C. Corr, Komal Kanojia, Konstantinos A. Kouremenos, David P. De Souza, Malcolm J. McConville, Richard A. Flavell, Motti Gerlic, Benjamin T. Kile, Anthony T. Papenfuss, Tracy L. Putoczki, Graham L. Radford-Smith, Seth L. Masters
Publicado 2018

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

por Joanne M. Hildebrand, Maria Kauppi, Ian J. Majewski, Zikou Liu, Allison J. Cox, Sanae Miyake, Emma J. Petrie, Michael A. Silk, Zhixiu Li, Maria C. Tanzer, Gabriela Brumatti, Samuel N. Young, Cathrine Hall, Sarah E. Garnish, Jason Corbin, Michael D. Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C. Josefsson, Kristin Rigbye, Holly Anderton, James A. Rickard, Anne Tripaydonis, Julie Sheridan, Thomas S. Scerri, Victoria E. Jackson, Peter E. Czabotar, Jian-Guo Zhang, Leila Varghese, Cody C. Allison, Marc Pellegrini, Gillian M. Tannahill, Esme C. Hatchell, Tracy A. Willson, Dina Stockwell, Carolyn A. de Graaf, Janelle Collinge, Adrienne Hilton, Natasha Silke, Sukhdeep K. Spall, Diep Chau, Vicki Athanasopoulos, Donald Metcalf, Ronald M. Laxer, Alexander G. Bassuk, Benjamin W. Darbro, Maria A. Fiatarone Singh, Nicole Vlahovich, David Hughes, Maria Kozlovskaia, David B. Ascher, Klaus Warnatz, Nils Venhoff, Jens Thiel, Christine Biben, Stefan Blum, John Reveille, Michael S. Hildebrand, Carola G. Vinuesa, Pamela McCombe, Matthew A. Brown, Benjamin T. Kile, Catriona McLean, Melanie Bahlo, Seth L. Masters, Hiroyasu Nakano, Polly J. Ferguson, James M. Murphy, Warren S. Alexander, John Silke
Publicado 2020