Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells

por Shiran Bar, Dan Vershkov, Gal Keshet, Elyad Lezmi, Naama Meller, Atilgan Yilmaz, Ofra Yanuka, Malka Nissim-Rafinia, Eran Meshorer, Talia Eldar-Geva, Nissim Benvenisty
Publicado 2021

Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

por Morten Dybdahl Krebs, Gonçalo Espregueira Themudo, Michael Eriksen Benros, Ole Mors, Anders D. Børglum, David Hougaard, Preben Bo Mortensen, Merete Nordentoft, Michael J. Gandal, Chun Chieh Fan, Daniel H. Geschwind, Andrew J. Schork, Thomas Werge, Wesley K. Thompson
Publicado 2021

A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus

por Qian-Ying Zhu, Sisi Shan, Jinfang Yu, Si-Ying Peng, Cong Sun, Yanan Zuo, Lan-Yi Zhong, Shu-Mei Yan, Xiao Zhang, Ziqing Yang, Yong-Jian Peng, Xuanling Shi, Su-Mei Cao, Xinquan Wang, Mu-Sheng Zeng, Linqi Zhang
Publicado 2021

scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

por Katharina T. Schmid, Barbara Höllbacher, Cristiana Cruceanu, Anika Böttcher, Heiko Lickert, Elisabeth B. Binder, Fabian J. Theis, Matthias Heinig
Publicado 2021

Homozygous duplication identified by whole genome sequencing causes LRBA deficiency

por Daniele Merico, Yehonatan Pasternak, Mehdi Zarrei, Edward J. Higginbotham, Bhooma Thiruvahindrapuram, Ori Scott, Jessica Willett-Pachul, Eyal Grunebaum, Julia Upton, Adelle Atkinson, Vy H. D. Kim, Elbay Aliyev, Khalid Fakhro, Stephen W. Scherer, Chaim M. Roifman
Publicado 2021

Inkjet-printed low-dimensional materials-based complementary electronic circuits on paper

por Irene Brunetti, Lorenzo Pimpolari, Silvia Conti, Robyn Worsley, Subimal Majee, Dmitry K. Polyushkin, Matthias Paur, Elisabetta Dimaggio, Giovanni Pennelli, Giuseppe Iannaccone, Massimo Macucci, Francesco Pieri, Thomas Mueller, Cinzia Casiraghi, Gianluca Fiori
Publicado 2021

Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism

por Katrin Strassburger, Marilena Lutz, Sandra Müller, Aurelio A. Teleman
Publicado 2021

Strong-field coherent control of isolated attosecond pulse generation

por Yudong Yang, Roland E. Mainz, Giulio Maria Rossi, Fabian Scheiba, Miguel A. Silva-Toledo, Phillip D. Keathley, Giovanni Cirmi, Franz X. Kärtner
Publicado 2021

Field-induced metal-to-insulator transition and colossal anisotropic magnetoresistance in a nearly Dirac material EuMnSb2

por Z. L. Sun, A. F. Wang, H. M. Mu, H. H. Wang, Z. F. Wang, T. Wu, Z. Y. Wang, X. Y. Zhou, X. H. Chen
Publicado 2021

Whole genome sequencing and in vitro splice assays reveal genetic causes for inherited retinal diseases

por Zeinab Fadaie, Laura Whelan, Tamar Ben-Yosef, Adrian Dockery, Zelia Corradi, Christian Gilissen, Lonneke Haer-Wigman, Jordi Corominas, Galuh D. N. Astuti, Laura de Rooij, L. Ingeborgh van den Born, Caroline C. W. Klaver, Carel B. Hoyng, Niamh Wynne, Emma S. Duignan, Paul F. Kenna, Frans P. M. Cremers, G. Jane Farrar, Susanne Roosing
Publicado 2021

Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation

por Meihua Jin, Hiroki Shiwaku, Hikari Tanaka, Takayuki Obita, Sakurako Ohuchi, Yuki Yoshioka, Xiaocen Jin, Kanoh Kondo, Kyota Fujita, Hidenori Homma, Kazuyuki Nakajima, Mineyuki Mizuguchi, Hitoshi Okazawa
Publicado 2021

BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities

por Keisuke Yaku, Sailesh Palikhe, Hironori Izumi, Tomoyuki Yoshida, Keisuke Hikosaka, Faisal Hayat, Mariam Karim, Tooba Iqbal, Yasuhito Nitta, Atsushi Sato, Marie E. Migaud, Katsuhiko Ishihara, Hisashi Mori, Takashi Nakagawa
Publicado 2021

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors

por Ryan J. Geusz, Allen Wang, Dieter K. Lam, Nicholas K. Vinckier, Konstantinos-Dionysios Alysandratos, David A. Roberts, Jinzhao Wang, Samy Kefalopoulou, Araceli Ramirez, Yunjiang Qiu, Joshua Chiou, Kyle J. Gaulton, Bing Ren, Darrell N. Kotton, Maike Sander
Publicado 2021

Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer

por Maximilian W. Schenk, Sam Humphrey, A. S. Md Mukarram Hossain, Mitchell Revill, Sarah Pearsall, Alice Lallo, Stewart Brown, Samuel Bratt, Melanie Galvin, Tine Descamps, Cong Zhou, Simon P. Pearce, Lynsey Priest, Michelle Greenhalgh, Anshuman Chaturvedi, Alastair Kerr, Fiona Blackhall, Caroline Dive, Kristopher K. Frese
Publicado 2021

Two-input protein logic gate for computation in living cells

por Yashavantha L. Vishweshwaraiah, Jiaxing Chen, Venkat R. Chirasani, Erdem D. Tabdanov, Nikolay V. Dokholyan
Publicado 2021

Fluid migrations and volcanic earthquakes from depolarized ambient noise

por S. Petrosino, L. De Siena
Publicado 2021

The role of cyclonic activity in tropical temperature-rainfall scaling

por Dominik Traxl, Niklas Boers, Aljoscha Rheinwalt, Bodo Bookhagen
Publicado 2021

Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration

por Atsuya Yaguchi, Mio Oshikawa, Go Watanabe, Hirotsugu Hiramatsu, Noriyuki Uchida, Chikako Hara, Naoko Kaneko, Kazunobu Sawamoto, Takahiro Muraoka, Itsuki Ajioka
Publicado 2021

Propagating wave in a fluid by coherent motion of 2D colloids

por Koki Sano, Xiang Wang, Zhifang Sun, Satoshi Aya, Fumito Araoka, Yasuo Ebina, Takayoshi Sasaki, Yasuhiro Ishida, Takuzo Aida
Publicado 2021

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

por Ghulam Hassan Dar, Cláudia C. Mendes, Wei-Li Kuan, Alfina A. Speciale, Mariana Conceição, André Görgens, Inna Uliyakina, Miguel J. Lobo, Wooi F. Lim, Samir EL Andaloussi, Imre Mäger, Thomas C. Roberts, Roger A. Barker, Deborah C. I. Goberdhan, Clive Wilson, Matthew J. A. Wood
Publicado 2021