Shape shifter: redirection of prolate phage capsid assembly by staphylococcal pathogenicity islands

por N’Toia C. Hawkins, James L. Kizziah, José R. Penadés, Terje Dokland
Publicado 2021

Sustained enzymatic activity and flow in crowded protein droplets

por Andrea Testa, Mirco Dindo, Aleksander A. Rebane, Babak Nasouri, Robert W. Style, Ramin Golestanian, Eric R. Dufresne, Paola Laurino
Publicado 2021

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

por András Tálas, Dorottya A. Simon, Péter I. Kulcsár, Éva Varga, Sarah L. Krausz, Ervin Welker
Publicado 2021

Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second messenger

por Shirin Fatma, Arpita Chakravarti, Xuankun Zeng, Raven H. Huang
Publicado 2021

Experimental quantum simulation of superradiant phase transition beyond no-go theorem via antisqueezing

por Xi Chen, Ze Wu, Min Jiang, Xin-You Lü, Xinhua Peng, Jiangfeng Du
Publicado 2021

RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer

por Olav Engebraaten, Christina Yau, Kristian Berg, Elin Borgen, Øystein Garred, Maria E. B. Berstad, Ane S. V. Fremstedal, Angela DeMichele, Laura van ’t Veer, Laura Esserman, Anette Weyergang
Publicado 2021

Correlation of SARS-CoV-2-breakthrough infections to time-from-vaccine

por Barak Mizrahi, Roni Lotan, Nir Kalkstein, Asaf Peretz, Galit Perez, Amir Ben-Tov, Gabriel Chodick, Sivan Gazit, Tal Patalon
Publicado 2021

Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial

por Amy S. Clark, Christina Yau, Denise M. Wolf, Emanuel F. Petricoin, Laura J. van ‘t Veer, Douglas Yee, Stacy L. Moulder, Anne M. Wallace, A. Jo Chien, Claudine Isaacs, Judy C. Boughey, Kathy S. Albain, Kathleen Kemmer, Barbara B. Haley, Hyo S. Han, Andres Forero-Torres, Anthony Elias, Julie E. Lang, Erin D. Ellis, Rachel Yung, Debu Tripathy, Rita Nanda, Julia D. Wulfkuhle, Lamorna Brown-Swigart, Rosa I. Gallagher, Teresa Helsten, Erin Roesch, Cheryl A. Ewing, Michael Alvarado, Erin P. Crane, Meredith Buxton, Julia L. Clennell, Melissa Paoloni, Smita M. Asare, Amy Wilson, Gillian L. Hirst, Ruby Singhrao, Katherine Steeg, Adam Asare, Jeffrey B. Matthews, Scott Berry, Ashish Sanil, Michelle Melisko, Jane Perlmutter, Hope S. Rugo, Richard B. Schwab, W. Fraser Symmans, Nola M. Hylton, Donald A. Berry, Laura J. Esserman, Angela M. DeMichele
Publicado 2021

Real-time observation of Cooper pair splitting showing strong non-local correlations

por Antti Ranni, Fredrik Brange, Elsa T. Mannila, Christian Flindt, Ville F. Maisi
Publicado 2021

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair

por Maria Pilar Sanchez-Bailon, Soo-Youn Choi, Elizabeth R. Dufficy, Karan Sharma, Gavin S. McNee, Emma Gunnell, Kelly Chiang, Debashish Sahay, Sarah Maslen, Grant S. Stewart, J. Mark Skehel, Ingrid Dreveny, Clare C. Davies
Publicado 2021

Crosstalk between CST and RPA regulates RAD51 activity during replication stress

por Kai-Hang Lei, Han-Lin Yang, Hao-Yen Chang, Hsin-Yi Yeh, Dinh Duc Nguyen, Tzu-Yu Lee, Xinxing Lyu, Megan Chastain, Weihang Chai, Hung-Wen Li, Peter Chi
Publicado 2021

Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates

por Helena Costa-Verdera, Fanny Collaud, Christopher R. Riling, Pauline Sellier, Jayme M. L. Nordin, G. Michael Preston, Umut Cagin, Julien Fabregue, Simon Barral, Maryse Moya-Nilges, Jacomina Krijnse-Locker, Laetitia van Wittenberghe, Natalie Daniele, Bernard Gjata, Jeremie Cosette, Catalina Abad, Marcelo Simon-Sola, Severine Charles, Mathew Li, Marco Crosariol, Tom Antrilli, William J. Quinn, David A. Gross, Olivier Boyer, Xavier M. Anguela, Sean M. Armour, Pasqualina Colella, Giuseppe Ronzitti, Federico Mingozzi
Publicado 2021

A Just Digital framework to ensure equitable achievement of the Sustainable Development Goals

por Katriona O’Sullivan, Serena Clark, Kevin Marshall, Malcolm MacLachlan
Publicado 2021

The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells

por Priyam Banerjee, Guan-Yu Xiao, Xiaochao Tan, Veronica J. Zheng, Lei Shi, Maria Neus Bota Rabassedas, Hou-fu Guo, Xin Liu, Jiang Yu, Lixia Diao, Jing Wang, William K. Russell, Jason Roszik, Chad J. Creighton, Jonathan M. Kurie
Publicado 2021

Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen

por Zhijian Li, Christoph Kuppe, Susanne Ziegler, Mingbo Cheng, Nazanin Kabgani, Sylvia Menzel, Martin Zenke, Rafael Kramann, Ivan G. Costa
Publicado 2021

Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data

por Georgette Tanner, David R. Westhead, Alastair Droop, Lucy F. Stead
Publicado 2021

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

por Rebecca Conners, Mathew McLaren, Urszula Łapińska, Kelly Sanders, M. Rhia L. Stone, Mark A. T. Blaskovich, Stefano Pagliara, Bertram Daum, Jasna Rakonjac, Vicki A. M. Gold
Publicado 2021

Higher intake of whole grains and dietary fiber are associated with lower risk of liver cancer and chronic liver disease mortality

por Xing Liu, Wanshui Yang, Jessica L. Petrick, Linda M. Liao, Weibing Wang, Na He, Peter T. Campbell, Zuo-Feng Zhang, Edward Giovannucci, Katherine A. McGlynn, Xuehong Zhang
Publicado 2021

A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii

por Thomas J. Bateman, Megha Shah, Timothy Pham Ho, Hyejin Esther Shin, Chuxi Pan, Greg Harris, Jamie E. Fegan, Epshita A. Islam, Sang Kyun Ahn, Yogesh Hooda, Scott D. Gray-Owen, Wangxue Chen, Trevor F. Moraes
Publicado 2021

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

por Aidan M. Fenix, Yuichiro Miyaoka, Alessandro Bertero, Steven M. Blue, Matthew J. Spindler, Kenneth K. B. Tan, Juan A. Perez-Bermejo, Amanda H. Chan, Steven J. Mayerl, Trieu D. Nguyen, Caitlin R. Russell, Paweena P. Lizarraga, Annie Truong, Po-Lin So, Aishwarya Kulkarni, Kashish Chetal, Shashank Sathe, Nathan J. Sniadecki, Gene W. Yeo, Charles E. Murry, Bruce R. Conklin, Nathan Salomonis
Publicado 2021