Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

por Thomas Kruse, Caroline Benz, Dimitriya H. Garvanska, Richard Lindqvist, Filip Mihalic, Fabian Coscia, Raviteja Inturi, Ahmed Sayadi, Leandro Simonetti, Emma Nilsson, Muhammad Ali, Johanna Kliche, Ainhoa Moliner Morro, Andreas Mund, Eva Andersson, Gerald McInerney, Matthias Mann, Per Jemth, Norman E. Davey, Anna K. Överby, Jakob Nilsson, Ylva Ivarsson
Publicado 2021

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

por Manabu Kusakabe, Ann Chong Sun, Kateryna Tyshchenko, Rachel Wong, Aastha Nanda, Claire Shanna, Samuel Gusscott, Elizabeth A. Chavez, Alireza Lorzadeh, Alice Zhu, Ainsleigh Hill, Stacy Hung, Scott Brown, Artem Babaian, Xuehai Wang, Robert A. Holt, Christian Steidl, Aly Karsan, R. Keith Humphries, Connie J. Eaves, Martin Hirst, Andrew P. Weng
Publicado 2019

Correction: Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb

por Emily A. Partridge, Marcus G. Davey, Matthew A. Hornick, Patrick E. McGovern, Ali Y. Mejaddam, Jesse D. Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C. Caskey, Theodore R. Weiland, Jiancheng Han, Alexander J. Schupper, James T. Connelly, Kevin C. Dysart, Jack Rychik, Holly L. Hedrick, William H. Peranteau, Alan W. Flake
Publicado 2017

An extra-uterine system to physiologically support the extreme premature lamb

por Emily A. Partridge, Marcus G. Davey, Matthew A. Hornick, Patrick E. McGovern, Ali Y. Mejaddam, Jesse D. Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C. Caskey, Theodore R. Weiland, Jiancheng Han, Alexander J. Schupper, James T. Connelly, Kevin C. Dysart, Jack Rychik, Holly L. Hedrick, William H. Peranteau, Alan W. Flake
Publicado 2017

Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions

por Martin G. Dalin, Nora Katabi, Marta Persson, Ken-Wing Lee, Vladimir Makarov, Alexis Desrichard, Logan A. Walsh, Lyndsay West, Zaineb Nadeem, Deepa Ramaswami, Jonathan J. Havel, Fengshen Kuo, Kalyani Chadalavada, Gouri J. Nanjangud, Ian Ganly, Nadeem Riaz, Alan L. Ho, Cristina R. Antonescu, Ronald Ghossein, Göran Stenman, Timothy A. Chan, Luc G. T. Morris
Publicado 2017

Large-scale phenotyping of 1,000 fungal strains for the degradation of non-natural, industrial compounds

por David Navarro, Delphine Chaduli, Sabine Taussac, Laurence Lesage-Meessen, Sacha Grisel, Mireille Haon, Philippe Callac, Régis Courtecuisse, Cony Decock, Joëlle Dupont, Florence Richard-Forget, Jacques Fournier, Jacques Guinberteau, Christian Lechat, Pierre-Arthur Moreau, Laetitia Pinson-Gadais, Bernard Rivoire, Lucile Sage, Stéphane Welti, Marie-Noëlle Rosso, Jean-Guy Berrin, Bastien Bissaro, Anne Favel
Publicado 2021

Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma

por Frank Riemer, Pippa G Corrie, Catherine Booth, Ferdia A Gallagher, Kevin M Brindle, Martin J Graves, Arthur Lewis, Doreen Lau, Mary A McLean, Andrew N Priest, Andrew B Gill, Francis Scott, Ilse Patterson, Bruno Carmo, Joshua D Kaggie, Amy Frary, Doreen Milne, Michal Sulikowski, Lee Brown, Jean-Martin Lapointe, Luigi Aloj
Publicado 2021

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

por Hélène Adihou, Ranganath Gopalakrishnan, Tim Förster, Stéphanie M. Guéret, Raphael Gasper, Stefan Geschwindner, Carmen Carrillo García, Hacer Karatas, Ajaybabu V. Pobbati, Mercedes Vazquez‐Chantada, Paul Davey, Carola M. Wassvik, Jeremy Kah Sheng Pang, Boon Seng Soh, Wanjin Hong, Elisabetta Chiarparin, Dennis Schade, Alleyn T. Plowright, Eric Valeur, Malin Lemurell, Tom N. Grossmann, Herbert Waldmann
Publicado 2020

Polymorphisms in DNA-repair genes in a cohort of prostate cancer patients from different areas in Spain: heterogeneity between populations as a confounding factor in association st...

por Luis Alberto Henríquez-Hernández, Almudena Valenciano, Palmira Foro-Arnalot, María Jesús Alvarez-Cubero, José Manuel Cozar, José Francisco Suárez-Novo, Manel Castells-Esteve, Adriana Ayala-Gil, Pablo Fernández-Gonzalo, Montse Ferrer, Ferrán Guedea, Gemma Sancho-Pardo, Jordi Craven-Bartle, María José Ortiz-Gordillo, Patricia Cabrera-Roldán, Estefanía Herrera-Ramos, Pedro C Lara
Publicado 2013

What are the most important unanswered research questions on rapid review methodology? A James Lind Alliance research methodology Priority Setting Partnership: the Priority III stu...

por Claire Beecher, Elaine Toomey, Beccy Maeso, Caroline Whiting, Derek C. Stewart, Andrew Worrall, Jim Elliott, Maureen Smith, Theresa Tierney, Bronagh Blackwood, Teresa Maguire, Melissa Kampman, Benny Ling, Christopher Gravel, Catherine Gill, Patricia Healy, Catherine Houghton, Andrew Booth, Chantelle Garritty, James Thomas, Andrea C. Tricco, Nikita N. Burke, Ciara Keenan, Matthew Westmore, Declan Devane
Publicado 2021

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

por Elizabeth C. Randall, Kristina B. Emdal, Janice K. Laramy, Minjee Kim, Alison Roos, David Calligaris, Michael S. Regan, Shiv K. Gupta, Ann C. Mladek, Brett L. Carlson, Aaron J. Johnson, Fa-Ke Lu, X. Sunney Xie, Brian A. Joughin, Raven J. Reddy, Sen Peng, Walid M. Abdelmoula, Pamela R. Jackson, Aarti Kolluri, Katherine A. Kellersberger, Jeffrey N. Agar, Douglas A. Lauffenburger, Kristin R. Swanson, Nhan L. Tran, William F. Elmquist, Forest M. White, Jann N. Sarkaria, Nathalie Y. R. Agar
Publicado 2018