Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling

por Joseph D Butner, Geoffrey V Martin, Zhihui Wang, Bruna Corradetti, Mauro Ferrari, Nestor Esnaola, Caroline Chung, David S Hong, James W Welsh, Naomi Hasegawa, Elizabeth A Mittendorf, Steven A Curley, Shu-Hsia Chen, Ping-Ying Pan, Steven K Libutti, Shridar Ganesan, Richard L Sidman, Renata Pasqualini, Wadih Arap, Eugene J Koay, Vittorio Cristini
Publicado 2021

Multisensory-motor integration in olfactory navigation of silkmoth, Bombyx mori, using virtual reality system

por Mayu Yamada, Hirono Ohashi, Koh Hosoda, Daisuke Kurabayashi, Shunsuke Shigaki
Publicado 2021

circFL-seq reveals full-length circular RNAs with rolling circular reverse transcription and nanopore sequencing

por Zelin Liu, Changyu Tao, Shiwei Li, Minghao Du, Yongtai Bai, Xueyan Hu, Yu Li, Jian Chen, Ence Yang
Publicado 2021

mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant

por Helen Parry, Gokhan Tut, Rachel Bruton, Sian Faustini, Christine Stephens, Philip Saunders, Christopher Bentley, Katherine Hilyard, Kevin Brown, Gayatri Amirthalingam, Sue Charlton, Stephanie Leung, Emily Chiplin, Naomi S Coombes, Kevin R Bewley, Elizabeth J Penn, Cathy Rowe, Ashley Otter, Rosie Watts, Silvia D'Arcangelo, Bassam Hallis, Andrew Makin, Alex Richter, Jianmin Zuo, Paul Moss
Publicado 2021

The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the mouse lateral amygdala via cholecystokinin

por Hemin Feng, Junfeng Su, Wei Fang, Xi Chen, Jufang He
Publicado 2021

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A2α

por Yoshinori Hirano, Yong-Guang Gao, Daniel J Stephenson, Ngoc T Vu, Lucy Malinina, Dhirendra K Simanshu, Charles E Chalfant, Dinshaw J Patel, Rhoderick E Brown
Publicado 2021

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A2α

por Yoshinori Hirano, Yong-Guang Gao, Daniel J Stephenson, Ngoc T Vu, Lucy Malinina, Dhirendra K Simanshu, Charles E Chalfant, Dinshaw J Patel, Rhoderick E Brown
Publicado 2019

Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans

por Ian F Price, Hannah L Hertz, Benjamin Pastore, Jillian Wagner, Wen Tang
Publicado 2021

Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis

por Andreas Hober, Khue Hua Tran-Minh, Dominic Foley, Thomas McDonald, Johannes PC Vissers, Rebecca Pattison, Samantha Ferries, Sigurd Hermansson, Ingvar Betner, Mathias Uhlén, Morteza Razavi, Richard Yip, Matthew E Pope, Terry W Pearson, Leigh N Andersson, Amy Bartlett, Lisa Calton, Jessica J Alm, Lars Engstrand, Fredrik Edfors
Publicado 2021

Why sex matters

por Josette J Wlaschin, Sangeetha Hareendran, Claire E Le Pichon
Publicado 2021

Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice

por Julia A Kuhn, Ilia D Vainchtein, Joao Braz, Katherine Hamel, Mollie Bernstein, Veronica Craik, Madelene W Dahlgren, Jorge Ortiz-Carpena, Ari B Molofsky, Anna V Molofsky, Allan I Basbaum
Publicado 2021

Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel

por Cathrine Bergh, Stephanie A Heusser, Rebecca Howard, Erik Lindahl
Publicado 2021

Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions

por Aixin Song, Zachary Hazlett, Dulith Abeykoon, Jeremy Dortch, Andrew Dillon, Justin Curtiss, Sarah Bollinger Martinez, Christopher P Hill, Clinton Yu, Lan Huang, David Fushman, Robert E Cohen, Tingting Yao
Publicado 2021

A nanocompartment system contributes to defense against oxidative stress in Mycobacterium tuberculosis

por Katie A Lien, Kayla Dinshaw, Robert J Nichols, Caleb Cassidy-Amstutz, Matthew Knight, Rahul Singh, Lindsay D Eltis, David F Savage, Sarah A Stanley
Publicado 2021

A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection

por Yansheng Li, Mingkai Xu, Yongqiang Li, Wu Gu, Gulinare Halimu, Yuqi Li, Zhichun Zhang, Libao Zhou, Hui Liao, Songyuan Yao, Huiwen Zhang, Chenggang Zhang
Publicado 2021

High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms

por Mathias Scharmann, Anthony G Rebelo, John R Pannell
Publicado 2021

Motor memories of object dynamics are categorically organized

por Evan Cesanek, Zhaoran Zhang, James N Ingram, Daniel M Wolpert, J Randall Flanagan
Publicado 2021

The alpha/B.1.1.7 SARS-CoV-2 variant exhibits significantly higher affinity for ACE-2 and requires lower inoculation doses to cause disease in K18-hACE2 mice

por Rafael Bayarri-Olmos, Laust Bruun Johnsen, Manja Idorn, Line S Reinert, Anne Rosbjerg, Søren Vang, Cecilie Bo Hansen, Charlotte Helgstrand, Jais Rose Bjelke, Theresa Bak-Thomsen, Søren R Paludan, Peter Garred, Mikkel-Ole Skjoedt
Publicado 2021

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

por Anirban Roy, Meiricris Tomaz da Silva, Raksha Bhat, Kyle R Bohnert, Takao Iwawaki, Ashok Kumar
Publicado 2021

Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor

por Anja Floeser, Katharina Becker, Evi Kostenis, Gabriele König, Cornelius Krasel, Peter Kolb, Moritz Buenemann
Publicado 2021