Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response.

por Amit Singh, David K Crossman, Deborah Mai, Loni Guidry, Martin I Voskuil, Matthew B Renfrow, Adrie J C Steyn
Publicado 2009

Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response

por Hylton E. Rodel, Hylton E. Rodel, Isabella A. T. M. Ferreira, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, Yashica Ganga, Mallory Bernstein, Shi-Hsia Hwa, Shi-Hsia Hwa, Kievershen Nargan, Gila Lustig, Gilla Kaplan, Mahdad Noursadeghi, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Adrie J. C. Steyn, Adrie J. C. Steyn, Adrie J. C. Steyn, Alex Sigal, Alex Sigal, Alex Sigal, Alex Sigal
Publicado 2021

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

por Dirk A. Lamprecht, Peter M. Finin, Md. Aejazur Rahman, Bridgette M. Cumming, Shannon L. Russell, Surendranadha R. Jonnala, John H. Adamson, Adrie J. C. Steyn
Publicado 2016

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

por Caroline S. Foo, Andréanne Lupien, Maryline Kienle, Anthony Vocat, Andrej Benjak, Raphael Sommer, Dirk A. Lamprecht, Adrie J. C. Steyn, Kevin Pethe, Jérémie Piton, Karl-Heinz Altmann, Stewart T. Cole
Publicado 2018

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

por Jared S. Mackenzie, Dirk A. Lamprecht, Rukaya Asmal, John H. Adamson, Khushboo Borah, Dany J. V. Beste, Bei Shi Lee, Kevin Pethe, Simon Rousseau, Inna Krieger, James C. Sacchettini, Joel N. Glasgow, Adrie J. C. Steyn
Publicado 2020

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

por Vikram Saini, Krishna C. Chinta, Vineel P. Reddy, Joel N. Glasgow, Asaf Stein, Dirk A. Lamprecht, Md. Aejazur Rahman, Jared S. Mackenzie, Barry E. Truebody, John H. Adamson, Tafara T. R. Kunota, Shannon M. Bailey, Douglas R. Moellering, Jack R. Lancaster, Adrie J. C. Steyn
Publicado 2020