Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2.

por Julia Diegelmann, Darina Czamara, Emmanuelle Le Bras, Eva Zimmermann, Torsten Olszak, Andrea Bedynek, Burkhard Göke, Andre Franke, Jürgen Glas, Stephan Brand
Publicado 2013

Iterative Sequencing and Variant Screening (ISVS) as a novel pathogenic mutations search strategy - application for TMPRSS3 mutations screen

por Urszula Lechowicz, Tomasz Gambin, Agnieszka Pollak, Anna Podgorska, Piotr Stawinski, Andre Franke, Britt-Sabina Petersen, Malgorzata Firczuk, Monika Oldak, Henryk Skarzynski, Rafal Ploski
Publicado 2017

A fungal pathogen induces systemic susceptibility and systemic shifts in wheat metabolome and microbiome composition

por Heike Seybold, Tobias J. Demetrowitsch, M. Amine Hassani, Silke Szymczak, Ekaterina Reim, Janine Haueisen, Luisa Lübbers, Malte Rühlemann, Andre Franke, Karin Schwarz, Eva H. Stukenbrock
Publicado 2020

Clinical correlates of anti-SARS-CoV-2 antibody profiles in Spanish COVID-19 patients from a high incidence region

por Robert Markewitz, Antje Torge, Klaus-Peter Wandinger, Daniela Pauli, Andre Franke, Luis Bujanda, José Maria Marimón, Jesus M. Banales, María A. Gutierrez-Stampa, Beatriz Nafría, Ralf Junker
Publicado 2021

BMI, Alcohol Consumption and Gut Microbiome Species Richness Are Related to Structural and Functional Neurological Abnormalities

por Corinna Geisler, Jil Pankoke, Kristina Schlicht, Carina Knappe, Nathalie Rohmann, Katharina Hartmann, Ute Settgast, Kathrin Türk, Anna Katharina Seoudy, Andre Franke, Stefan Schreiber, Dominik M. Schulte, Matthias Laudes
Publicado 2021

Effect of various weight loss interventions on serum NT-proBNP concentration in severe obese subjects without clinical manifest heart failure

por Tim Hollstein, Kristina Schlicht, Laura Krause, Stefanie Hagen, Nathalie Rohmann, Dominik M. Schulte, Kathrin Türk, Alexia Beckmann, Markus Ahrens, Andre Franke, Stefan Schreiber, Thomas Becker, Jan Beckmann, Matthias Laudes
Publicado 2021

Carrying asymptomatic gallstones is not associated with changes in intestinal microbiota composition and diversity but cholecystectomy with significant dysbiosis

por Fabian Frost, Tim Kacprowski, Malte Rühlemann, Stefan Weiss, Corinna Bang, Andre Franke, Maik Pietzner, Ali A. Aghdassi, Matthias Sendler, Uwe Völker, Henry Völzke, Julia Mayerle, Frank U. Weiss, Georg Homuth, Markus M. Lerch
Publicado 2021

Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.

por Agne Liedén, Mårten C G Winge, Annika Sääf, Ingrid Kockum, Elisabeth Ekelund, Elke Rodriguez, Regina Fölster-Holst, Andre Franke, Thomas Illig, Maria Tengvall-Linder, Hansjörg Baurecht, Stephan Weidinger, Carl-Fredrik Wahlgren, Magnus Nordenskjöld, Maria Bradley
Publicado 2012

Genetic Variation in <i>ABCC4</i> and <i>CFTR</i> and Acute Pancreatitis during Treatment of Pediatric Acute Lymphoblastic Leukemia

por Thies Bartram, Peter Schütte, Anja Möricke, Richard S. Houlston, Eva Ellinghaus, Martin Zimmermann, Anke Bergmann, Britt-Sabina Löscher, Norman Klein, Laura Hinze, Stefanie V. Junk, Michael Forster, Claus R. Bartram, Rolf Köhler, Andre Franke, Martin Schrappe, Christian P. Kratz, Gunnar Cario, Martin Stanulla
Publicado 2021

A genome-wide analysis of populations from European Russia reveals a new pole of genetic diversity in northern Europe.

por Andrey V Khrunin, Denis V Khokhrin, Irina N Filippova, Tõnu Esko, Mari Nelis, Natalia A Bebyakova, Natalia L Bolotova, Janis Klovins, Liene Nikitina-Zake, Karola Rehnström, Samuli Ripatti, Stefan Schreiber, Andre Franke, Milan Macek, Veronika Krulišová, Jan Lubinski, Andres Metspalu, Svetlana A Limborska
Publicado 2013

Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis

por Nuria Pell, Ester Garcia-Pras, Javier Gallego, Salvador Naranjo-Suarez, Alexandra Balvey, Clara Suñer, Marcos Fernandez-Alfara, Veronica Chanes, Julia Carbo, Marta Ramirez-Pedraza, Oscar Reina, Louise Thingholm, Corinna Bang, Malte Rühlemann, Andre Franke, Robert Schierwagen, Karl P. Rheinwalt, Jonel Trebicka, Raul Mendez, Mercedes Fernandez
Publicado 2021

Methotrexate Treatment of Newly Diagnosed RA Patients Is Associated With DNA Methylation Differences at Genes Relevant for Disease Pathogenesis and Pharmacological Action

por Kari Guderud, Kari Guderud, Line H. Sunde, Line H. Sunde, Siri T. Flåm, Siri T. Flåm, Marthe T. Mæhlen, Maria D. Mjaavatten, Ellen S. Norli, Ida M. Evenrød, Bettina K. Andreassen, Sören Franzenburg, Andre Franke, Simon Rayner, Kristina Gervin, Kristina Gervin, Kristina Gervin, Benedicte A. Lie, Benedicte A. Lie
Publicado 2021

Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry

por Alexander Immel, Federica Pierini, Christoph Rinne, John Meadows, Rodrigo Barquera, András Szolek, Julian Susat, Lisa Böhme, Janina Dose, Joanna Bonczarowska, Clara Drummer, Katharina Fuchs, David Ellinghaus, Jan Christian Kässens, Martin Furholt, Oliver Kohlbacher, Sabine Schade-Lindig, Andre Franke, Stefan Schreiber, Johannes Krause, Johannes Müller, Tobias L. Lenz, Almut Nebel, Ben Krause-Kyora
Publicado 2021

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

por Ben Krause-Kyora, Marcel Nutsua, Lisa Boehme, Federica Pierini, Dorthe Dangvard Pedersen, Sabin-Christin Kornell, Dmitriy Drichel, Marion Bonazzi, Lena Möbus, Peter Tarp, Julian Susat, Esther Bosse, Beatrix Willburger, Alexander H. Schmidt, Jürgen Sauter, Andre Franke, Michael Wittig, Amke Caliebe, Michael Nothnagel, Stefan Schreiber, Jesper L. Boldsen, Tobias L. Lenz, Almut Nebel
Publicado 2018

Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide

por Philip E. Stuart, Lam C. Tsoi, Rajan P. Nair, Manju Ghosh, Madhulika Kabra, Pakeeza A. Shaiq, Ghazala K. Raja, Raheel Qamar, B.K. Thelma, Matthew T. Patrick, Anita Parihar, Sonam Singh, Sujay Khandpur, Uma Kumar, Michael Wittig, Frauke Degenhardt, Trilokraj Tejasvi, John J. Voorhees, Stephan Weidinger, Andre Franke, Goncalo R. Abecasis, Vinod K. Sharma, James T. Elder
Publicado 2022

Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease

por Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Publicado 2019

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients

por Matthew T. Patrick, Philip E. Stuart, Kalpana Raja, Johann E. Gudjonsson, Trilokraj Tejasvi, Jingjing Yang, Vinod Chandran, Sayantan Das, Kristina Callis-Duffin, Eva Ellinghaus, Charlotta Enerbäck, Tõnu Esko, Andre Franke, Hyun M. Kang, Gerald G. Krueger, Henry W. Lim, Proton Rahman, Cheryl F. Rosen, Stephan Weidinger, Michael Weichenthal, Xiaoquan Wen, John J. Voorhees, Gonçalo R. Abecasis, Dafna D. Gladman, Rajan P. Nair, James T. Elder, Lam C. Tsoi
Publicado 2018

Identification and characterization of two functional variants in the human longevity gene FOXO3

por Friederike Flachsbart, Janina Dose, Liljana Gentschew, Claudia Geismann, Amke Caliebe, Carolin Knecht, Marianne Nygaard, Nandini Badarinarayan, Abdou ElSharawy, Sandra May, Anne Luzius, Guillermo G. Torres, Marlene Jentzsch, Michael Forster, Robert Häsler, Kathrin Pallauf, Wolfgang Lieb, Céline Derbois, Pilar Galan, Dmitriy Drichel, Alexander Arlt, Andreas Till, Ben Krause-Kyora, Gerald Rimbach, Hélène Blanché, Jean-François Deleuze, Lene Christiansen, Kaare Christensen, Michael Nothnagel, Philip Rosenstiel, Stefan Schreiber, Andre Franke, Susanne Sebens, Almut Nebel
Publicado 2017

Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3

por Friederike Flachsbart, Janina Dose, Liljana Gentschew, Claudia Geismann, Amke Caliebe, Carolin Knecht, Marianne Nygaard, Nandini Badarinarayan, Abdou ElSharawy, Sandra May, Anne Luzius, Guillermo G. Torres, Marlene Jentzsch, Michael Forster, Robert Häsler, Kathrin Pallauf, Wolfgang Lieb, Céline Derbois, Pilar Galan, Dmitriy Drichel, Alexander Arlt, Andreas Till, Ben Krause-Kyora, Gerald Rimbach, Hélène Blanché, Jean-François Deleuze, Lene Christiansen, Kaare Christensen, Michael Nothnagel, Philip Rosenstiel, Stefan Schreiber, Andre Franke, Susanne Sebens, Almut Nebel
Publicado 2018

Digital Media Exposure and Predictors for Screen Time in 12-Month-Old Children: A Cross-Sectional Analysis of Data From a German Birth Cohort

por Kira Durham, David Wethmar, Susanne Brandstetter, Susanne Brandstetter, Birgit Seelbach-Göbel, Christian Apfelbacher, Christian Apfelbacher, Michael Melter, Michael Kabesch, Sebastian Kerzel, The KUNO Kids Study Group, Andreas Ambrosch, Petra Arndt, Andrea Baessler, Mark Berneburg, Stephan Böse-O'Reilly, Romuald Brunner, Wolfgang Buchalla, Sara Fill Malfertheiner, Sebastian Häusler, André Franke, Iris Heid, Caroline Herr, Wolfgang Högler, Sebastian Kerzel, Michael Koller, Michael Leitzmann, David Rothfuß, Wolfgang Rösch, Bianca Schaub, Bernhard H.F. Weber, Stephan Weidinger, Sven Wellman
Publicado 2021