Phosphorylation-dependent BRD4 dimerization and implications for therapeutic inhibition of BET family proteins

par Francesca Malvezzi, Christopher J. Stubbs, Thomas A. Jowitt, Ian L. Dale, Xieyang Guo, Jon P. DeGnore, Gianluca Degliesposti, J. Mark Skehel, Andrew J. Bannister, Mark S. McAlister
Publié 2021

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

par Konstantinos Tzelepis, Etienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M. S. Vijayabaskar, Wen-Hsin Liu, Malgorzata Gozdecka, Emmanouil Metzakopian, Hamish D. Toop, Monika Dudek, Samuel C. Robson, Francisco Hermida-Prado, Yu Hsuen Yang, Roya Babaei-Jadidi, Dimitrios A. Garyfallos, Hannes Ponstingl, Joao M. L. Dias, Paolo Gallipoli, Michael Seiler, Silvia Buonamici, Binje Vick, Andrew J. Bannister, Roland Rad, Rab K. Prinjha, John C. Marioni, Brian Huntly, Jennifer Batson, Jonathan C. Morris, Cristina Pina, Allan Bradley, Irmela Jeremias, David O. Bates, Kosuke Yusa, Tony Kouzarides, George S. Vassiliou
Publié 2018