Protein truncating variants in FANCM and risk for ER-negative/triple negative breast cancer

por Paolo Peterlongo, Gisella Figlioli, Andrew J. Deans, Fergus J. Couch
Publicado 2021

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

por Bruno Silva, Richard Pentz, Ana Margarida Figueira, Rajika Arora, Yong Woo Lee, Charlotte Hodson, Harry Wischnewski, Andrew J. Deans, Claus M. Azzalin
Publicado 2019

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

por Robert Lu, Julienne J. O’Rourke, Alexander P. Sobinoff, Joshua A. M. Allen, Christopher B. Nelson, Christopher G. Tomlinson, Michael Lee, Roger R. Reddel, Andrew J. Deans, Hilda A. Pickett
Publicado 2019

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

por Robert Lu, Julienne J. O’Rourke, Alexander P. Sobinoff, Joshua A. M. Allen, Christopher B. Nelson, Christopher G. Tomlinson, Michael Lee, Roger R. Reddel, Andrew J. Deans, Hilda A. Pickett
Publicado 2019

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

por Elaine Sanij, Katherine M. Hannan, Jiachen Xuan, Shunfei Yan, Jessica E. Ahern, Anna S. Trigos, Natalie Brajanovski, Jinbae Son, Keefe T. Chan, Olga Kondrashova, Elizabeth Lieschke, Matthew J. Wakefield, Daniel Frank, Sarah Ellis, Carleen Cullinane, Jian Kang, Gretchen Poortinga, Purba Nag, Andrew J. Deans, Kum Kum Khanna, Linda Mileshkin, Grant A. McArthur, John Soong, Els M. J. J. Berns, Ross D. Hannan, Clare L. Scott, Karen E. Sheppard, Richard B. Pearson
Publicado 2020