Metabolic Plasticity in Melanoma Progression and Response to Oncogene Targeted Therapies

por Arwa Alkaraki, Grant A. McArthur, Karen E. Sheppard, Lorey K. Smith
Publicado 2021

Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

por Shahneen Sandhu, Grant A McArthur, Kate Drummond, Alison Weppler, Tony Papenfuss, Amir Iravani, Belinda Lee, Richard J Young, Kortnye Smith, Peter Kar Han Lau, Breon Feran, Lorey Smith, Arian Lasocki, Ramyar Molania, Christopher Angel, Hanxian Aw Yeang, Ismael A Vergara, David Kok, Paul Joseph Neeson, Karen E Sheppard, Benjamin J Solomon
Publicado 2021

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

por Elaine Sanij, Katherine M. Hannan, Jiachen Xuan, Shunfei Yan, Jessica E. Ahern, Anna S. Trigos, Natalie Brajanovski, Jinbae Son, Keefe T. Chan, Olga Kondrashova, Elizabeth Lieschke, Matthew J. Wakefield, Daniel Frank, Sarah Ellis, Carleen Cullinane, Jian Kang, Gretchen Poortinga, Purba Nag, Andrew J. Deans, Kum Kum Khanna, Linda Mileshkin, Grant A. McArthur, John Soong, Els M. J. J. Berns, Ross D. Hannan, Clare L. Scott, Karen E. Sheppard, Richard B. Pearson
Publicado 2020