Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization

por Ruili Huang, Menghang Xia, Srilatha Sakamuru, Jinghua Zhao, Sampada A. Shahane, Matias Attene-Ramos, Tongan Zhao, Christopher P. Austin, Anton Simeonov
Publicado 2016

Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

por Hu Zhu, Catherine Z. Chen, Srilatha Sakamuru, Jinghua Zhao, Deborah K. Ngan, Anton Simeonov, Mathew D. Hall, Menghang Xia, Wei Zheng, Ruili Huang
Publicado 2021

Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

por Dorjbal Dorjsuren, Richard T. Eastman, Kathryn J. Wicht, Daniel Jansen, Daniel C. Talley, Benjamin A. Sigmon, Alexey V. Zakharov, Norma Roncal, Andrew T. Girvin, Yevgeniya Antonova-Koch, Paul M. Will, Pranav Shah, Hongmao Sun, Carleen Klumpp-Thomas, Sachel Mok, Tomas Yeo, Stephan Meister, Juan Jose Marugan, Leila S. Ross, Xin Xu, David J. Maloney, Ajit Jadhav, Bryan T. Mott, Richard J. Sciotti, Elizabeth A. Winzeler, Norman C. Waters, Robert F. Campbell, Wenwei Huang, Anton Simeonov, David A. Fidock
Publicado 2021