Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase.

por Matthäus Getlik, Jeffrey R Simard, Martin Termathe, Christian Grütter, Matthias Rabiller, Willem A L van Otterlo, Daniel Rauh
Publicado 2012

Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling.

por Martin Peifer, Jonathan Weiss, Martin L Sos, Mirjam Koker, Stefanie Heynck, Christian Netzer, Stefanie Fischer, Haridas Rode, Daniel Rauh, Jörg Rahnenführer, Roman K Thomas
Publicado 2010

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

por Lena Quambusch, Laura Depta, Ina Landel, Melissa Lubeck, Tonia Kirschner, Jonas Nabert, Niklas Uhlenbrock, Jörn Weisner, Michael Kostka, Laura M. Levy, Carsten Schultz-Fademrecht, Franziska Glanemann, Kristina Althoff, Matthias P. Müller, Jens T. Siveke, Daniel Rauh
Publicado 2021

Overcoming EGFR G724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors

por Jana Fassunke, Fabienne Müller, Marina Keul, Sebastian Michels, Marcel A. Dammert, Anna Schmitt, Dennis Plenker, Jonas Lategahn, Carina Heydt, Johannes Brägelmann, Hannah L. Tumbrink, Yannic Alber, Sebastian Klein, Alena Heimsoeth, Ilona Dahmen, Rieke N. Fischer, Matthias Scheffler, Michaela A. Ihle, Vanessa Priesner, Andreas H. Scheel, Svenja Wagener, Anna Kron, Konrad Frank, Katia Garbert, Thorsten Persigehl, Michael Püsken, Stefan Haneder, Bernhard Schaaf, Ernst Rodermann, Walburga Engel-Riedel, Enriqueta Felip, Egbert F. Smit, Sabine Merkelbach-Bruse, H. Christian Reinhardt, Stefan M. Kast, Jürgen Wolf, Daniel Rauh, Reinhard Büttner, Martin L. Sos
Publicado 2018