Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers

by David H. Peng, B. Leticia Rodriguez, Lixia Diao, Pierre-Olivier Gaudreau, Aparna Padhye, Jessica M. Konen, Joshua K. Ochieng, Caleb A. Class, Jared J. Fradette, Laura Gibson, Limo Chen, Jing Wang, Lauren A. Byers, Don. L. Gibbons
Published 2021

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion

by David H. Peng, Bertha Leticia Rodriguez, Lixia Diao, Limo Chen, Jing Wang, Lauren A. Byers, Ying Wei, Harold A. Chapman, Mitsuo Yamauchi, Carmen Behrens, Gabriela Raso, Luisa Maren Solis Soto, Edwin Roger Parra Cuentes, Ignacio I. Wistuba, Jonathan M. Kurie, Don L. Gibbons
Published 2020

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer

by Roxsan Manshouri, Etienne Coyaud, Samrat T. Kundu, David H. Peng, Sabrina A. Stratton, Kendra Alton, Rakhee Bajaj, Jared J. Fradette, Rosalba Minelli, Michael D. Peoples, Alessandro Carugo, Fengju Chen, Christopher Bristow, Jeffrey J. Kovacs, Michelle C. Barton, Tim Heffernan, Chad J. Creighton, Brian Raught, Don L. Gibbons
Published 2019

Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma

by Yun-Fan Sun, Liang Wu, Shi-Ping Liu, Miao-Miao Jiang, Bo Hu, Kai-Qian Zhou, Wei Guo, Yang Xu, Yu Zhong, Xiao-Rui Zhou, Ze-Fan Zhang, Geng Liu, Sheng Liu, Ying-Hong Shi, Yuan Ji, Min Du, Nan-Nan Li, Gui-Bo Li, Zhi-Kun Zhao, Xiao-Yun Huang, Li-Qin Xu, Qi-Chao Yu, David H. Peng, Shuang-Jian Qiu, Hui-Chuan Sun, Michael Dean, Xiang-Dong Wang, Wen-Yuan Chung, Ashley R. Dennison, Jian Zhou, Yong Hou, Jia Fan, Xin-Rong Yang
Published 2021