Competition for nutrients and its role in controlling immune responses

por Nidhi Kedia-Mehta, David K. Finlay
Publicado 2019

Glucose represses dendritic cell-induced T cell responses

por Simon J. Lawless, Nidhi Kedia-Mehta, Jessica F. Walls, Ryan McGarrigle, Orla Convery, Linda V. Sinclair, Maria N. Navarro, James Murray, David K. Finlay
Publicado 2017

Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation

por Nicholas Jones, Emma E. Vincent, James G. Cronin, Silvia Panetti, Megan Chambers, Sean R. Holm, Sian E. Owens, Nigel J. Francis, David K. Finlay, Catherine A. Thornton
Publicado 2019

TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

por Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner
Publicado 2021

Metabolic requirements of NK cells during the acute response against retroviral infection

por Elisabeth Littwitz-Salomon, Diana Moreira, Joe N. Frost, Chloe Choi, Kevin T. Liou, David K. Ahern, Simon O’Shaughnessy, Bernd Wagner, Christine A. Biron, Hal Drakesmith, Ulf Dittmer, David K. Finlay
Publicado 2021

Specific human cytomegalovirus signature detected in NK cell metabolic changes post vaccination

por Elena Woods, Vanessa Zaiatz-Bittencourt, Ciaran Bannan, Colm Bergin, David K. Finlay, Matthias Hoffmann, Anthony Brown, Bethany Turner, Shokouh Makvandi-Nejad, Ventzi Vassilev, Stefania Capone, Antonella Folgori, Tomáš Hanke, Eleanor Barnes, Lucy Dorrell, Clair M. Gardiner, PEACHI Consortium
Publicado 2021

The Circadian Clock Protein BMAL1 Acts as a Metabolic Sensor In Macrophages to Control the Production of Pro IL-1β

por George A. Timmons, Richard G. Carroll, James R. O’Siorain, Mariana P. Cervantes-Silva, Lauren E. Fagan, Shannon L. Cox, Eva Palsson-McDermott, David K. Finlay, Emma E. Vincent, Emma E. Vincent, Nicholas Jones, Annie M. Curtis
Publicado 2021

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

por Róisín M. Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie L. O’Brien, Arianne Garcia, Conor Gillespie, Jens L. Hukelmann, Peter J. Oefner, Angus I. Lamond, Clair M. Gardiner, Katja Dettmer, Doreen A. Cantrell, Linda V. Sinclair, David K. Finlay
Publicado 2018

Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation

por Nicholas Jones, Julianna Blagih, Fabio Zani, April Rees, David G. Hill, Benjamin J. Jenkins, Caroline J. Bull, Diana Moreira, Azari I. M. Bantan, James G. Cronin, Daniele Avancini, Gareth W. Jones, David K. Finlay, Karen H. Vousden, Emma E. Vincent, Catherine A. Thornton
Publicado 2021

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

por Jennifer K. Dowling, Remsha Afzal, Linden J. Gearing, Mariana P. Cervantes-Silva, Stephanie Annett, Gavin M. Davis, Chiara De Santi, Nadine Assmann, Katja Dettmer, Daniel J. Gough, Glenn R. Bantug, Fidinny I. Hamid, Frances K. Nally, Conor P. Duffy, Aoife L. Gorman, Alex M. Liddicoat, Ed C. Lavelle, Christoph Hess, Peter J. Oefner, David K. Finlay, Gavin P. Davey, Tracy Robson, Annie M. Curtis, Paul J. Hertzog, Bryan R. G. Williams, Claire E. McCoy
Publicado 2021