Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

por Alessandra Lopes, Kevin Vanvarenberg, Špela Kos, Sophie Lucas, Didier Colau, Benoît Van den Eynde, Véronique Préat, Gaëlle Vandermeulen
Publicado 2018

Regulatory T cells control toxicity in a humanized model of IL-2 therapy

por Yan Li, Helene Strick-Marchand, Ai Ing Lim, Jiazi Ren, Guillemette Masse-Ranson, Dan Li, Gregory Jouvion, Lars Rogge, Sophie Lucas, Bin Li, James P. Di Santo
Publicado 2017

TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

por Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner
Publicado 2021

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer

por Grégoire de Streel, Charlotte Bertrand, Nicolas Chalon, Stéphanie Liénart, Orian Bricard, Sara Lecomte, Julien Devreux, Mélanie Gaignage, Gitte De Boeck, Lore Mariën, Inge Van De Walle, Bas van der Woning, Michael Saunders, Hans de Haard, Elien Vermeersch, Wim Maes, Hans Deckmyn, Pierre G. Coulie, Nicolas van Baren, Sophie Lucas
Publicado 2020