Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity

par Simone Joas, Erica H. Parrish, Clement W. Gnanadurai, Edina Lump, Christina M. Stürzel, Nicholas F. Parrish, Gerald H. Learn, Ulrike Sauermann, Berit Neumann, Kerstin Mätz Rensing, Dietmar Fuchs, James M. Billingsley, Steven E. Bosinger, Guido Silvestri, Cristian Apetrei, Nicolas Huot, Thalia Garcia-Tellez, Michaela Müller-Trutwin, Dominik Hotter, Daniel Sauter, Christiane Stahl-Hennig, Beatrice H. Hahn, Frank Kirchhoff
Publié 2018

Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.

par Nicholas F Parrish, Craig B Wilen, Lauren B Banks, Shilpa S Iyer, Jennifer M Pfaff, Jesus F Salazar-Gonzalez, Maria G Salazar, Julie M Decker, Erica H Parrish, Anna Berg, Jennifer Hopper, Bhavna Hora, Amit Kumar, Tatenda Mahlokozera, Sally Yuan, Charl Coleman, Marion Vermeulen, Haitao Ding, Christina Ochsenbauer, John C Tilton, Sallie R Permar, John C Kappes, Michael R Betts, Michael P Busch, Feng Gao, David Montefiori, Barton F Haynes, George M Shaw, Beatrice H Hahn, Robert W Doms
Publié 2012