Stromal down-regulation of macrophage CD4/CCR5 expression and NF-κB activation mediates HIV-1 non-permissiveness in intestinal macrophages.

por Ruizhong Shen, Gang Meng, Christina Ochsenbauer, Paul R Clapham, Jayleen Grams, Lea Novak, John C Kappes, Lesley E Smythies, Phillip D Smith
Publicado 2011

Mice transgenic for CD4-specific human CD4, CCR5 and cyclin T1 expression: a new model for investigating HIV-1 transmission and treatment efficacy.

por Kieran Seay, Xiaohua Qi, Jian Hua Zheng, Cong Zhang, Ken Chen, Monica Dutta, Kathryn Deneroff, Christina Ochsenbauer, John C Kappes, Dan R Littman, Harris Goldstein
Publicado 2013

Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.

por Nicholas F Parrish, Craig B Wilen, Lauren B Banks, Shilpa S Iyer, Jennifer M Pfaff, Jesus F Salazar-Gonzalez, Maria G Salazar, Julie M Decker, Erica H Parrish, Anna Berg, Jennifer Hopper, Bhavna Hora, Amit Kumar, Tatenda Mahlokozera, Sally Yuan, Charl Coleman, Marion Vermeulen, Haitao Ding, Christina Ochsenbauer, John C Tilton, Sallie R Permar, John C Kappes, Michael R Betts, Michael P Busch, Feng Gao, David Montefiori, Barton F Haynes, George M Shaw, Beatrice H Hahn, Robert W Doms
Publicado 2012