Posttranslational chemical installation of azoles into translated peptides

por Haruka Tsutsumi, Tomohiro Kuroda, Hiroyuki Kimura, Yuki Goto, Hiroaki Suga
Publicado 2021

Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling

por Takayuki Katoh, Ingo Wohlgemuth, Masanobu Nagano, Marina V. Rodnina, Hiroaki Suga
Publicado 2016

Minimal lactazole scaffold for in vitro thiopeptide bioengineering

por Alexander A. Vinogradov, Morito Shimomura, Yuki Goto, Taro Ozaki, Shumpei Asamizu, Yoshinori Sugai, Hiroaki Suga, Hiroyasu Onaka
Publicado 2020

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

por Yamato Komatsu, Naohiro Terasaka, Katsuya Sakai, Emiko Mihara, Risa Wakabayashi, Kunio Matsumoto, Donald Hilvert, Junichi Takagi, Hiroaki Suga
Publicado 2021

Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo

por Taro Ozaki, Kona Yamashita, Yuki Goto, Morito Shimomura, Shohei Hayashi, Shumpei Asamizu, Yoshinori Sugai, Haruo Ikeda, Hiroaki Suga, Hiroyasu Onaka
Publicado 2017

Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins

por Emiko Mihara, Satoshi Watanabe, Nasir K. Bashiruddin, Nozomi Nakamura, Kyoko Matoba, Yumi Sano, Rumit Maini, Yizhen Yin, Katsuya Sakai, Takao Arimori, Kunio Matsumoto, Hiroaki Suga, Junichi Takagi
Publicado 2021

Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases

por Hao Yu, Patricia Dranchak, Zhiru Li, Ryan MacArthur, Matthew S. Munson, Nurjahan Mehzabeen, Nathan J. Baird, Kevin P. Battalie, David Ross, Scott Lovell, Clotilde K. S. Carlow, Hiroaki Suga, James Inglese
Publicado 2017

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

por Akane Kawamura, Martin Münzel, Tatsuya Kojima, Clarence Yapp, Bhaskar Bhushan, Yuki Goto, Anthony Tumber, Takayuki Katoh, Oliver N. F. King, Toby Passioura, Louise J. Walport, Stephanie B. Hatch, Sarah Madden, Susanne Müller, Paul E. Brennan, Rasheduzzaman Chowdhury, Richard J. Hopkinson, Hiroaki Suga, Christopher J. Schofield
Publicado 2017

Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models

por Makoto Saito, Yasushi Itoh, Fumihiko Yasui, Tsubasa Munakata, Daisuke Yamane, Makoto Ozawa, Risa Ito, Takayuki Katoh, Hirohito Ishigaki, Misako Nakayama, Shintaro Shichinohe, Kenzaburo Yamaji, Naoki Yamamoto, Ai Ikejiri, Tomoko Honda, Takahiro Sanada, Yoshihiro Sakoda, Hiroshi Kida, Thi Quynh Mai Le, Yoshihiro Kawaoka, Kazumasa Ogasawara, Kyoko Tsukiyama-Kohara, Hiroaki Suga, Michinori Kohara
Publicado 2021