Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase

por Kei Kudo, Takehiro Nishimura, Ikuko Kozone, Junko Hashimoto, Noritaka Kagaya, Hikaru Suenaga, Haruo Ikeda, Kazuo Shin-ya
Publicado 2021

In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

por Kei Kudo, Takuya Hashimoto, Junko Hashimoto, Ikuko Kozone, Noritaka Kagaya, Reiko Ueoka, Takehiro Nishimura, Mamoru Komatsu, Hikaru Suenaga, Haruo Ikeda, Kazuo Shin-ya
Publicado 2020