Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

por Jason J. Zoeller, Roderick T. Bronson, Laura M. Selfors, Gordon B. Mills, Joan S. Brugge
Publicado 2017

Clinical evaluation of BCL-2/XL levels pre- and post- HER2-targeted therapy.

por Jason J Zoeller, Michael F Press, Laura M Selfors, Judy Dering, Dennis J Slamon, Sara A Hurvitz, Joan S Brugge
Publicado 2021

Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response

por Ioannis K. Zervantonakis, Claudia Iavarone, Hsing-Yu Chen, Laura M. Selfors, Sangeetha Palakurthi, Joyce F. Liu, Ronny Drapkin, Ursula Matulonis, Joel D. Leverson, Deepak Sampath, Gordon B. Mills, Joan S. Brugge
Publicado 2017

Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages

por Jennifer M. Rosenbluth, Ron C. J. Schackmann, G. Kenneth Gray, Laura M. Selfors, Carman Man-Chung Li, Mackenzie Boedicker, Hendrik J. Kuiken, Andrea Richardson, Jane Brock, Judy Garber, Deborah Dillon, Norman Sachs, Hans Clevers, Joan S. Brugge
Publicado 2020

Transient commensal clonal interactions can drive tumor metastasis

por Suha Naffar-Abu Amara, Hendrik J. Kuiken, Laura M. Selfors, Timothy Butler, Marco L. Leung, Cheuk T. Leung, Elaine P. Kuhn, Teodora Kolarova, Carina Hage, Kripa Ganesh, Richard Panayiotou, Rosemary Foster, Bo R. Rueda, Athena Aktipis, Paul Spellman, Tan A. Ince, Joanne Xiu, Matthew Oberley, Zoran Gatalica, Nicholas Navin, Gordon B. Mills, Rodrick T. Bronson, Joan S. Brugge
Publicado 2020