Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria

by Pierre Santucci, Matt D. Johansen, Vanessa Point, Isabelle Poncin, Albertus Viljoen, Jean-François Cavalier, Laurent Kremer, Stéphane Canaan
Published 2019

Acetic Acid, the Active Component of Vinegar, Is an Effective Tuberculocidal Disinfectant

by Claudia Cortesia, Catherine Vilchèze, Audrey Bernut, Whendy Contreras, Keyla Gómez, Jacobus de Waard, William R. Jacobs, Laurent Kremer, Howard Takiff
Published 2014

Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline.

by Jaryd R Sullivan, Andréanne Lupien, Elias Kalthoff, Claire Hamela, Lorne Taylor, Kim A Munro, T Martin Schmeing, Laurent Kremer, Marcel A Behr
Published 2021

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

by Dhinakaran Sambandan, Dee N. Dao, Brian C. Weinrick, Catherine Vilchèze, Sudagar S. Gurcha, Anil Ojha, Laurent Kremer, Gurdyal S. Besra, Graham F. Hatfull, William R. Jacobs
Published 2013

Phosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosis.

by Catherine Vilchèze, Virginie Molle, Séverine Carrère-Kremer, Jade Leiba, Lionel Mourey, Shubhada Shenai, Grégory Baronian, Joann Tufariello, Travis Hartman, Romain Veyron-Churlet, Xavier Trivelli, Sangeeta Tiwari, Brian Weinrick, David Alland, Yann Guérardel, William R Jacobs, Laurent Kremer
Published 2014

Identification of KasA as the cellular target of an anti-tubercular scaffold

by Katherine A. Abrahams, Chun-wa Chung, Sonja Ghidelli-Disse, Joaquín Rullas, María José Rebollo-López, Sudagar S. Gurcha, Jonathan A. G. Cox, Alfonso Mendoza, Elena Jiménez-Navarro, María Santos Martínez-Martínez, Margarete Neu, Anthony Shillings, Paul Homes, Argyrides Argyrou, Ruth Casanueva, Nicholas J. Loman, Patrick J. Moynihan, Joël Lelièvre, Carolyn Selenski, Matthew Axtman, Laurent Kremer, Marcus Bantscheff, Iñigo Angulo-Barturen, Mónica Cacho Izquierdo, Nicholas C. Cammack, Gerard Drewes, Lluis Ballell, David Barros, Gurdyal S. Besra, Robert H. Bates
Published 2016