ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes

por Kenan C. Murphy, Samantha J. Nelson, Subhalaxmi Nambi, Kadamba Papavinasasundaram, Christina E. Baer, Christopher M. Sassetti
Publicado 2018

Modeling Site-Specific Nucleotide Biases Affecting Himar1 Transposon Insertion Frequencies in TnSeq Data Sets

por Sanjeevani Choudhery, A. Jacob Brown, Chidiebere Akusobi, Eric J. Rubin, Christopher M. Sassetti, Thomas R. Ioerger
Publicado 2021

Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

por Michelle M. Bellerose, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, Christopher M. Sassetti
Publicado 2020

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

por Michael C Kiritsy, Katelyn McCann, Daniel Mott, Steven M Holland, Samuel M Behar, Christopher M Sassetti, Andrew J Olive
Publicado 2021

An improved statistical method to identify chemical-genetic interactions by exploiting concentration-dependence.

por Esha Dutta, Michael A DeJesus, Nadine Ruecker, Anisha Zaveri, Eun-Ik Koh, Christopher M Sassetti, Dirk Schnappinger, Thomas R Ioerger
Publicado 2021

Relaxation and revival of quasiparticles injected in an interacting quantum Hall liquid

por R. H. Rodriguez, F. D. Parmentier, D. Ferraro, P. Roulleau, U. Gennser, A. Cavanna, M. Sassetti, F. Portier, D. Mailly, P. Roche
Publicado 2020

Sirtuin 3 Downregulation in <i>Mycobacterium tuberculosis</i> -Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death

por Lorissa J. Smulan, Nuria Martinez, Michael C. Kiritsy, Chido Kativhu, Kelly Cavallo, Christopher M. Sassetti, Amit Singhal, Heinz G. Remold, Hardy Kornfeld
Publicado 2021

Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during <italic toggle="yes">Mycobacterium tuberculosis</italic> Infection

por Alissa C. Rothchild, Britni Stowell, Girija Goyal, Cláudio Nunes-Alves, Qianting Yang, Kadamba Papavinasasundaram, Christopher M. Sassetti, Glenn Dranoff, Xinchun Chen, Jinhee Lee, Samuel M. Behar
Publicado 2017

Allele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibility.

por Guoliang Zhang, Boping Zhou, Shaoyuan Li, Jun Yue, Hui Yang, Yuxin Wen, Senlin Zhan, Wenfei Wang, Mingfeng Liao, Mingxia Zhang, Gucheng Zeng, Carl G Feng, Christopher M Sassetti, Xinchun Chen
Publicado 2014

Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice

por Clare M. Smith, Megan K. Proulx, Rocky Lai, Michael C. Kiritsy, Timothy A. Bell, Pablo Hock, Fernando Pardo-Manuel de Villena, Martin T. Ferris, Richard E. Baker, Samuel M. Behar, Christopher M. Sassetti
Publicado 2019

Comprehensive Essentiality Analysis of the <italic toggle="yes">Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis

por Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger
Publicado 2017

Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy

por Michelle M. Bellerose, Seung-Hun Baek, Chuan-Chin Huang, Caitlin E. Moss, Eun-Ik Koh, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Jong Seok Lee, Seokyong Eum, Sung Jae Shin, Sang-Nae Cho, Megan Murray, Christopher M. Sassetti
Publicado 2019

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

por Clare M. Smith, Megan K. Proulx, Andrew J. Olive, Dominick Laddy, Bibhuti B. Mishra, Caitlin Moss, Nuria Martinez Gutierrez, Michelle M. Bellerose, Palmira Barreira-Silva, Jia Yao Phuah, Richard E. Baker, Samuel M. Behar, Hardy Kornfeld, Thomas G. Evans, Gillian Beamer, Christopher M. Sassetti
Publicado 2016