Dynamic diagnosis of familial prion diseases supports the β2-α2 loop as a universal interference target.

por Massimiliano Meli, Maria Gasset, Giorgio Colombo
Publicado 2011

Revealing Escherichia coli type II l-asparaginase active site flexible loop in its open, ligand-free conformation

por Maristella Maggi, Massimiliano Meli, Giorgio Colombo, Claudia Scotti
Publicado 2021

Investigating the dynamic aspects of drug-protein recognition through a combination of MD and NMR analyses: implications for the development of protein-protein interaction inhibito...

por Massimiliano Meli, Katiuscia Pagano, Laura Ragona, Giorgio Colombo
Publicado 2014

Methionine sulfoxides on prion protein Helix-3 switch on the alpha-fold destabilization required for conversion.

por Giorgio Colombo, Massimiliano Meli, Giulia Morra, Ruth Gabizon, María Gasset
Publicado 2009

A multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide GNNQQNY from the yeast prion sup-35.

por Jessica Nasica-Labouze, Massimiliano Meli, Philippe Derreumaux, Giorgio Colombo, Normand Mousseau
Publicado 2011

The five-to-six-coordination transition of ferric human serum heme-albumin is allosterically-modulated by ibuprofen and warfarin: a combined XAS and MD study.

por Carlo Meneghini, Loris Leboffe, Monica Bionducci, Gabriella Fanali, Massimiliano Meli, Giorgio Colombo, Mauro Fasano, Paolo Ascenzi, Settimio Mobilio
Publicado 2014