When is hub gene selection better than standard meta-analysis?

par Peter Langfelder, Paul S Mischel, Steve Horvath
Publié 2013

Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling

par Feng Liu, Paul S. Mischel, Webster K. Cavenee
Publié 2017

BAP1 methylation: a prognostic marker of uveal melanoma metastasis

par Mathieu F. Bakhoum, Ellis J. Curtis, Michael H. Goldbaum, Paul S. Mischel
Publié 2021

Challenges in identifying cancer genes by analysis of exome sequencing data

par Matan Hofree, Hannah Carter, Jason F. Kreisberg, Sourav Bandyopadhyay, Paul S. Mischel, Stephen Friend, Trey Ideker
Publié 2016

Exploring the landscape of focal amplifications in cancer using AmpliconArchitect

par Viraj Deshpande, Jens Luebeck, Nam-Phuong D. Nguyen, Mehrdad Bakhtiari, Kristen M. Turner, Richard Schwab, Hannah Carter, Paul S. Mischel, Vineet Bafna
Publié 2019

AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications

par Jens Luebeck, Ceyda Coruh, Siavash R. Dehkordi, Joshua T. Lange, Kristen M. Turner, Viraj Deshpande, Dave A. Pai, Chao Zhang, Utkrisht Rajkumar, Julie A. Law, Paul S. Mischel, Vineet Bafna
Publié 2020

A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.

par Renee D Read, Tim R Fenton, German G Gomez, Jill Wykosky, Scott R Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K Cavenee, Paul S Mischel, Frank B Furnari, John B Thomas
Publié 2013

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression

par Mathieu F. Bakhoum, Jasmine H. Francis, Albert Agustinus, Ethan M. Earlie, Melody Di Bona, David H. Abramson, Mercedes Duran, Ignas Masilionis, Elsa Molina, Alexander N. Shoushtari, Michael H. Goldbaum, Paul S. Mischel, Samuel F. Bakhoum, Ashley M. Laughney
Publié 2021

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

par Tomoyuki Koga, Isaac A. Chaim, Jorge A. Benitez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner, Kristen M. Turner, Florian M. Hessenauer, Matteo D’Antonio, Nam-phuong D. Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D. Boyer, John Ravits, Kelly A. Frazer, Vineet Bafna, Clark C. Chen, Paul S. Mischel, Gene W. Yeo, Frank B. Furnari
Publié 2020

Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

par Tomoyuki Koga, Isaac A. Chaim, Jorge A. Benitez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner, Kristen M. Turner, Florian M. Hessenauer, Matteo D’Antonio, Nam-phuong D. Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D. Boyer, John Ravits, Kelly A. Frazer, Vineet Bafna, Clark C. Chen, Paul S. Mischel, Gene W. Yeo, Frank B. Furnari
Publié 2020

Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

par Junfeng Bi, Atif Khan, Jun Tang, Aaron M. Armando, Sihan Wu, Wei Zhang, Ryan C. Gimple, Alex Reed, Hui Jing, Tomoyuki Koga, Ivy Tsz-Lo Wong, Yuchao Gu, Shunichiro Miki, Huijun Yang, Briana Prager, Ellis J. Curtis, Derek A. Wainwright, Frank B. Furnari, Jeremy N. Rich, Timothy F. Cloughesy, Harley I. Kornblum, Oswald Quehenberger, Andrey Rzhetsky, Benjamin F. Cravatt, Paul S. Mischel
Publié 2021