Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

por Tina Skjørringe, Per Amstrup Pedersen, Sidsel Salling Thorborg, Poul Nissen, Pontus Gourdon, Lisbeth Birk Møller
Publicado 2017

Large scale identification and categorization of protein sequences using structured logistic regression.

por Bjørn P Pedersen, Georgiana Ifrim, Poul Liboriussen, Kristian B Axelsen, Michael G Palmgren, Poul Nissen, Carsten Wiuf, Christian N S Pedersen
Publicado 2014

A conserved leucine occupies the empty substrate site of LeuT in the Na+-free return state

por Lina Malinauskaite, Saida Said, Caglanur Sahin, Julie Grouleff, Azadeh Shahsavar, Henriette Bjerregaard, Pernille Noer, Kasper Severinsen, Thomas Boesen, Birgit Schiøtt, Steffen Sinning, Poul Nissen
Publicado 2016

Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases

por Jacob Lauwring Andersen, Borbala Gesser, Erik Daa Funder, Christine Juul Fælled Nielsen, Helle Gotfred-Rasmussen, Mads Kirchheiner Rasmussen, Rachel Toth, Kurt Vesterager Gothelf, J. Simon C. Arthur, Lars Iversen, Poul Nissen
Publicado 2018

X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

por Kamil Gotfryd, Thomas Boesen, Jonas S. Mortensen, George Khelashvili, Matthias Quick, Daniel S. Terry, Julie W. Missel, Michael V. LeVine, Pontus Gourdon, Scott C. Blanchard, Jonathan A. Javitch, Harel Weinstein, Claus J. Loland, Poul Nissen, Ulrik Gether
Publicado 2020