A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

por Junqiao Du, Kuok Yap, Lai Yue Chan, Fabian B. H. Rehm, Fong Yang Looi, Aaron G. Poth, Edward K. Gilding, Quentin Kaas, Thomas Durek, David J. Craik
Publicado 2020

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity

por Joshua S. Wingerd, Christine A. Mozar, Christine A. Ussing, Swetha S. Murali, Yanni K.-Y. Chin, Ben Cristofori-Armstrong, Thomas Durek, John Gilchrist, Christopher W. Vaughan, Frank Bosmans, David J. Adams, Richard J. Lewis, Paul F. Alewood, Mehdi Mobli, Macdonald J. Christie, Lachlan D. Rash
Publicado 2017