The Impact of Histological Annotations for Accurate Tissue Classification Using Mass Spectrometry Imaging

by Juliana Pereira Lopes Gonçalves, Christine Bollwein, Anna Melissa Schlitter, Benedikt Martin, Bruno Märkl, Kirsten Utpatel, Wilko Weichert, Kristina Schwamborn
Published 2021

A Mass Spectrometry Imaging Based Approach for Prognosis Prediction in UICC Stage I/II Colon Cancer

by Benedikt Martin, Juliana P. L. Gonçalves, Christine Bollwein, Florian Sommer, Gerhard Schenkirsch, Anne Jacob, Armin Seibert, Wilko Weichert, Bruno Märkl, Kristina Schwamborn
Published 2021

Histopathological Tumor and Normal Tissue Responses after 3D-Planned Arc Radiotherapy in an Orthotopic Xenograft Mouse Model of Human Pancreatic Cancer

by Sophie Dobiasch, Severin Kampfer, Katja Steiger, Daniela Schilling, Julius C. Fischer, Thomas E. Schmid, Wilko Weichert, Jan J. Wilkens, Stephanie E. Combs
Published 2021

Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast cancer

by Aurelia Noske, Daniel-Christoph Wagner, Kristina Schwamborn, Sebastian Foersch, Katja Steiger, Marion Kiechle, Dirk Oettler, Siranush Karapetyan, Alexander Hapfelmeier, Wilfried Roth, Wilko Weichert
Published 2021

Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma

by Na Sun, Marija Trajkovic-Arsic, Fengxia Li, Yin Wu, Corinna Münch, Thomas Kunzke, Annette Feuchtinger, Katja Steiger, Anna Melissa Schlitter, Wilko Weichert, Irene Esposito, Jens T. Siveke, Axel Walch
Published 2021

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

by Marc Rosenbaum, Andreas Gewies, Konstanze Pechloff, Christoph Heuser, Thomas Engleitner, Torben Gehring, Lara Hartjes, Sabrina Krebs, Daniel Krappmann, Mark Kriegsmann, Wilko Weichert, Roland Rad, Christian Kurts, Jürgen Ruland
Published 2019

Who is at risk for diagnostic discrepancies? Comparison of pre- and postmortal diagnoses in 1800 patients of 3 medical decades in East and West Berlin.

by Daniel Wittschieber, Frederick Klauschen, Anna-Christin Kimmritz, Moritz von Winterfeld, Carsten Kamphues, Hans-Joachim Scholman, Andreas Erbersdobler, Heidi Pfeiffer, Carsten Denkert, Manfred Dietel, Wilko Weichert, Jan Budczies, Albrecht Stenzinger
Published 2012

Proteome activity landscapes of tumor cell lines determine drug responses

by Martin Frejno, Chen Meng, Benjamin Ruprecht, Thomas Oellerich, Sebastian Scheich, Karin Kleigrewe, Enken Drecoll, Patroklos Samaras, Alexander Hogrebe, Dominic Helm, Julia Mergner, Jana Zecha, Stephanie Heinzlmeir, Mathias Wilhelm, Julia Dorn, Hans-Michael Kvasnicka, Hubert Serve, Wilko Weichert, Bernhard Kuster
Published 2020

Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes.

by Christof Winter, Glen Kristiansen, Stephan Kersting, Janine Roy, Daniela Aust, Thomas Knösel, Petra Rümmele, Beatrix Jahnke, Vera Hentrich, Felix Rückert, Marco Niedergethmann, Wilko Weichert, Marcus Bahra, Hans J Schlitt, Utz Settmacher, Helmut Friess, Markus Büchler, Hans-Detlev Saeger, Michael Schroeder, Christian Pilarsky, Robert Grützmann
Published 2012

Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma

by Melanie Boxberg, Katja Steiger, Wilko Weichert, Roland Rad, Kai Yu, Sebastian Lange, Thomas Engleitner, Huan Lan, Eva Bräunlein, Gaia Lupoli, Franziska Füchsl, Esam T Abualrous, Niklas de Andrade Krätzig, Dario Gosmann, Lukas Wietbrock, Stefan Audehm, Manuel Effenberger, Yinshui Chang, Cigdem Atay, Florian Bassermann, Dirk H Busch, Christian Freund, Iris Antes, Angela M Krackhardt
Published 2021

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer

by Soulafa Mamlouk, Liam Harold Childs, Daniela Aust, Daniel Heim, Friederike Melching, Cristiano Oliveira, Thomas Wolf, Pawel Durek, Dirk Schumacher, Hendrik Bläker, Moritz von Winterfeld, Bastian Gastl, Kerstin Möhr, Andrea Menne, Silke Zeugner, Torben Redmer, Dido Lenze, Sascha Tierling, Markus Möbs, Wilko Weichert, Gunnar Folprecht, Eric Blanc, Dieter Beule, Reinhold Schäfer, Markus Morkel, Frederick Klauschen, Ulf Leser, Christine Sers
Published 2017

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

by Enkhtsetseg Munkhbaatar, Michelle Dietzen, Deepti Agrawal, Martina Anton, Moritz Jesinghaus, Melanie Boxberg, Nicole Pfarr, Pidassa Bidola, Sebastian Uhrig, Ulrike Höckendorf, Anna-Lena Meinhardt, Adam Wahida, Irina Heid, Rickmer Braren, Ritu Mishra, Arne Warth, Thomas Muley, Patrina S. P. Poh, Xin Wang, Stefan Fröhling, Katja Steiger, Julia Slotta-Huspenina, Martijn van Griensven, Franz Pfeiffer, Sebastian Lange, Roland Rad, Magda Spella, Georgios T. Stathopoulos, Jürgen Ruland, Florian Bassermann, Wilko Weichert, Andreas Strasser, Caterina Branca, Mathias Heikenwalder, Charles Swanton, Nicholas McGranahan, Philipp J. Jost
Published 2020

Defective homologous recombination DNA repair as therapeutic target in advanced chordoma

by Stefan Gröschel, Daniel Hübschmann, Francesco Raimondi, Peter Horak, Gregor Warsow, Martina Fröhlich, Barbara Klink, Laura Gieldon, Barbara Hutter, Kortine Kleinheinz, David Bonekamp, Oliver Marschal, Priya Chudasama, Jagoda Mika, Marie Groth, Sebastian Uhrig, Stephen Krämer, Christoph Heining, Christoph E. Heilig, Daniela Richter, Eva Reisinger, Katrin Pfütze, Roland Eils, Stephan Wolf, Christof von Kalle, Christian Brandts, Claudia Scholl, Wilko Weichert, Stephan Richter, Sebastian Bauer, Roland Penzel, Evelin Schröck, Albrecht Stenzinger, Richard F. Schlenk, Benedikt Brors, Robert B. Russell, Hanno Glimm, Matthias Schlesner, Stefan Fröhling
Published 2019

Integrative genomic and transcriptomic analysis of leiomyosarcoma

by Priya Chudasama, Sadaf S. Mughal, Mathijs A. Sanders, Daniel Hübschmann, Inn Chung, Katharina I. Deeg, Siao-Han Wong, Sophie Rabe, Mario Hlevnjak, Marc Zapatka, Aurélie Ernst, Kortine Kleinheinz, Matthias Schlesner, Lina Sieverling, Barbara Klink, Evelin Schröck, Remco M. Hoogenboezem, Bernd Kasper, Christoph E. Heilig, Gerlinde Egerer, Stephan Wolf, Christof von Kalle, Roland Eils, Albrecht Stenzinger, Wilko Weichert, Hanno Glimm, Stefan Gröschel, Hans-Georg Kopp, Georg Omlor, Burkhard Lehner, Sebastian Bauer, Simon Schimmack, Alexis Ulrich, Gunhild Mechtersheimer, Karsten Rippe, Benedikt Brors, Barbara Hutter, Marcus Renner, Peter Hohenberger, Claudia Scholl, Stefan Fröhling
Published 2018