Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells

por Jeong Hyun Lee, Laura Toy, Justin T. Kos, Yana Safonova, William R. Schief, Colin Havenar-Daughton, Corey T. Watson, Shane Crotty
Publicado 2021

Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development.

por Sowmya Sampath, Chris Carrico, Joel Janes, Sairam Gurumoorthy, Claire Gibson, Martin Melcher, Chetan E Chitnis, Ruobing Wang, William R Schief, Joseph D Smith
Publicado 2013

Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25

por Brandon McLeod, Kazutoyo Miura, Stephen W. Scally, Alexandre Bosch, Ngan Nguyen, Hanjun Shin, Dongkyoon Kim, Wayne Volkmuth, Sebastian Rämisch, Jessica A. Chichester, Stephen Streatfield, Colleen Woods, William R. Schief, Daniel Emerling, C. Richter King, Jean-Philippe Julien
Publicado 2019

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice

por Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic, Alexander D. Gitlin, Natalia T. Freund, John Petersen, Colin Correnti, William Johnsen, Robert Kegel, Andrew B. Stuart, Jolene Glenn, Michael S. Seaman, William R. Schief, Roland K. Strong, Michel C. Nussenzweig, Leonidas Stamatatos
Publicado 2016

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25

por Stephen W. Scally, Brandon McLeod, Alexandre Bosch, Kazutoyo Miura, Qi Liang, Sean Carroll, Sini Reponen, Ngan Nguyen, Eldar Giladi, Sebastian Rämisch, Vidadi Yusibov, Allan Bradley, Franck Lemiale, William R. Schief, Daniel Emerling, Paul Kellam, C. Richter King, Jean-Philippe Julien
Publicado 2017

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

por Liwei Cao, Matthias Pauthner, Raiees Andrabi, Kimmo Rantalainen, Zachary Berndsen, Jolene K. Diedrich, Sergey Menis, Devin Sok, Raiza Bastidas, Sung-Kyu Robin Park, Claire M. Delahunty, Lin He, Javier Guenaga, Richard T. Wyatt, William R. Schief, Andrew B. Ward, John R. Yates, Dennis R. Burton, James C. Paulson
Publicado 2018

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

por Liwei Cao, Jolene K. Diedrich, Daniel W. Kulp, Matthias Pauthner, Lin He, Sung-Kyu Robin Park, Devin Sok, Ching Yao Su, Claire M. Delahunty, Sergey Menis, Raiees Andrabi, Javier Guenaga, Erik Georgeson, Michael Kubitz, Yumiko Adachi, Dennis R. Burton, William R. Schief, John R. Yates III, James C. Paulson
Publicado 2017

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

por Daniel W. Kulp, Jon M. Steichen, Matthias Pauthner, Xiaozhen Hu, Torben Schiffner, Alessia Liguori, Christopher A. Cottrell, Colin Havenar-Daughton, Gabriel Ozorowski, Erik Georgeson, Oleksandr Kalyuzhniy, Jordan R. Willis, Michael Kubitz, Yumiko Adachi, Samantha M. Reiss, Mia Shin, Natalia de Val, Andrew B. Ward, Shane Crotty, Dennis R. Burton, William R. Schief
Publicado 2017

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

por Aleksandar Antanasijevic, Leigh M. Sewall, Christopher A. Cottrell, Diane G. Carnathan, Luis E. Jimenez, Julia T. Ngo, Jennifer B. Silverman, Bettina Groschel, Erik Georgeson, Jinal Bhiman, Raiza Bastidas, Celia LaBranche, Joel D. Allen, Jeffrey Copps, Hailee R. Perrett, Kimmo Rantalainen, Fabien Cannac, Yuhe R. Yang, Alba Torrents de la Peña, Rebeca Froes Rocha, Zachary T. Berndsen, David Baker, Neil P. King, Rogier W. Sanders, John P. Moore, Shane Crotty, Max Crispin, David C. Montefiori, Dennis R. Burton, William R. Schief, Guido Silvestri, Andrew B. Ward
Publicado 2021