Author Correction: Structure-based design and discovery of novel anti-tissue factor antibodies with cooperative double-point mutations, using interaction analysis

por Shuntaro Chiba, Aki Tanabe, Makoto Nakakido, Yasushi Okuno, Kouhei Tsumoto, Masateru Ohta
Publicado 2021

Dynamic changes in gene-to-gene regulatory networks in response to SARS-CoV-2 infection

por Yoshihisa Tanaka, Kako Higashihara, Mai Adachi Nakazawa, Fumiyoshi Yamashita, Yoshinori Tamada, Yasushi Okuno
Publicado 2021

Exploring ligand binding pathways on proteins using hypersound-accelerated molecular dynamics

por Mitsugu Araki, Shigeyuki Matsumoto, Gert-Jan Bekker, Yuta Isaka, Yukari Sagae, Narutoshi Kamiya, Yasushi Okuno
Publicado 2021

Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer

por Ken Uchibori, Naohiko Inase, Mitsugu Araki, Mayumi Kamada, Shigeo Sato, Yasushi Okuno, Naoya Fujita, Ryohei Katayama
Publicado 2017

Health improvement framework for actionable treatment planning using a surrogate Bayesian model

por Kazuki Nakamura, Ryosuke Kojima, Eiichiro Uchino, Koh Ono, Motoko Yanagita, Koichi Murashita, Ken Itoh, Shigeyuki Nakaji, Yasushi Okuno
Publicado 2021

A secondary RET mutation in the activation loop conferring resistance to vandetanib

por Takashi Nakaoku, Takashi Kohno, Mitsugu Araki, Seiji Niho, Rakhee Chauhan, Phillip P. Knowles, Katsuya Tsuchihara, Shingo Matsumoto, Yoko Shimada, Sachiyo Mimaki, Genichiro Ishii, Hitoshi Ichikawa, Satoru Nagatoishi, Kouhei Tsumoto, Yasushi Okuno, Kiyotaka Yoh, Neil Q. McDonald, Koichi Goto
Publicado 2018

Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity

por Takahiro Yoshizawa, Ken Uchibori, Mitsugu Araki, Shigeyuki Matsumoto, Biao Ma, Ryo Kanada, Yosuke Seto, Tomoko Oh-hara, Sumie Koike, Ryo Ariyasu, Satoru Kitazono, Hironori Ninomiya, Kengo Takeuchi, Noriko Yanagitani, Satoshi Takagi, Kazuma Kishi, Naoya Fujita, Yasushi Okuno, Makoto Nishio, Ryohei Katayama
Publicado 2021

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer

por Hayato Mizuta, Koutaroh Okada, Mitsugu Araki, Jun Adachi, Ai Takemoto, Justyna Kutkowska, Kohei Maruyama, Noriko Yanagitani, Tomoko Oh-hara, Kana Watanabe, Keiichi Tamai, Luc Friboulet, Kazuhiro Katayama, Biao Ma, Yoko Sasakura, Yukari Sagae, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Satoshi Takagi, Siro Simizu, Makoto Nishio, Yasushi Okuno, Naoya Fujita, Ryohei Katayama
Publicado 2021