Dissecting the molecular evolution of fluoroquinolone-resistant Shigella sonnei

Dissecting the molecular evolution of fluoroquinolone-resistant Shigella sonnei

Shigella sonnei is one of the main species causing shigellosis worldwide. Here the authors analyse nearly 400 S. sonnei genome sequences and carry out experimental evolution experiments to shed light into the evolutionary processes underlying the recent emergence of fluoroquinolone resistance in thi...

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Autores principales: Hao Chung The, Christine Boinett, Duy Pham Thanh, Claire Jenkins, Francois-Xavier Weill, Benjamin P. Howden, Mary Valcanis, Niall De Lappe, Martin Cormican, Sonam Wangchuk, Ladaporn Bodhidatta, Carl J. Mason, To Nguyen Thi Nguyen, Tuyen Ha Thanh, Vinh Phat Voong, Vu Thuy Duong, Phu Huong Lan Nguyen, Paul Turner, Ryan Wick, Pieter-Jan Ceyssens, Guy Thwaites, Kathryn E. Holt, Nicholas R. Thomson, Maia A. Rabaa, Stephen Baker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/02e39349172244c286f76e940e3e3054
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Sumario:Shigella sonnei is one of the main species causing shigellosis worldwide. Here the authors analyse nearly 400 S. sonnei genome sequences and carry out experimental evolution experiments to shed light into the evolutionary processes underlying the recent emergence of fluoroquinolone resistance in this pathogen.

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