A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
When DNA interstrand cross-links damage occurs, it causes disruption of replication and transcription. Here the authors identify FAM120B/SAN1, a 5′ exonuclease involved in the repair process of Interstrand Crosslinks independently of the Fanconi Anemia pathway.
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/031ac7b17c8c4e12a4254e48a3e6d6a6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|