Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice
The mechanism by which caffeine, an antagonist of adenosine receptors, regulates metabolism is not clear. Here the authors show that adenosine A1R receptor expression is increased in the hypothalamus of diet-induced obesity mice, and that body weight can be alleviated by central administration of ca...
Saved in:
| Main Authors: | Liufeng Wu, Jia Meng, Qing Shen, Yi Zhang, Susu Pan, Zhuo Chen, Ling-Qiang Zhu, Youming Lu, Yuan Huang, Guo Zhang |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/0330342e5f7e48ee99ed295bb8642fea |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice
by: Susu Pan, et al.
Published: (2021) -
DLK1 is a somato-dendritic protein expressed in hypothalamic arginine-vasopressin and oxytocin neurons.
by: Carine Villanueva, et al.
Published: (2012) -
Plasticity of intrinsic excitability across the estrous cycle in hypothalamic CRH neurons
by: Emmet M. Power, et al.
Published: (2021) -
Oxytocin administration suppresses hypothalamic activation in response to visual food cues
by: Agatha A. van der Klaauw, et al.
Published: (2017) -
NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
by: Wenwen Cheng, et al.
Published: (2021)