Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor
Summary: Myeloid-derived suppressor cells (MDSCs) enhance the proliferation of endothelial cells to stimulate angiogenesis. However, many aggressive malignant tumors do not have endothelial cell-dependent blood vessels in the early stage and instead generate microcirculation by forming vasculogenic...
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Main Authors: | Yinan Li, Kailiang Qiao, Xiaoyun Zhang, Haoyang Liu, Heng Zhang, Zhiyang Li, Yanrong Liu, Tao Sun |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Online Access: | https://doaj.org/article/12d4e99362da4897a3f0cb8d90ba9f52 |
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