BH3-only proteins Puma and Beclin1 regulate autophagic death in neurons in response to Amyloid-β

Abstract Alzheimer’s disease (AD) is characterized by accumulation of senile amyloid-β (Aβ) plaques and hyperphosphorylated tau tangles causing progressive loss of synapse and neuronal death. Out of the various neuron death modalities, autophagy and apoptosis are reported to be the major death parad...

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Bibliographic Details
Main Authors: Akash Saha, Suraiya Saleem, Paidi Ramesh Kumar, Subhas C. Biswas
Format: article
Language:EN
Published: Nature Publishing Group 2021
Subjects:
Online Access:https://doaj.org/article/131fddba260544bba6cd6f9e074fe80b
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