Mapping the kinetic barriers of a Large RNA molecule's folding landscape.
The folding of linear polymers into discrete three-dimensional structures is often required for biological function. The formation of long-lived intermediates is a hallmark of the folding of large RNA molecules due to the ruggedness of their energy landscapes. The precise thermodynamic nature of the...
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Main Authors: | Jörg C Schlatterer, Joshua S Martin, Alain Laederach, Michael Brenowitz |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/1396c9de73b34f869f75aa23b2caea99 |
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