Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E. coli.

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Autores principales:	Le Yu, Wenting Zhou, Yixuan She, Hongmin Ma, You-Sheng Cai, Ming Jiang, Zixin Deng, Neil P. J. Price, Wenqing Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1a017a78f5e242bfab6c97b66db75c86
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spelling	oai:doaj.org-article:1a017a78f5e242bfab6c97b66db75c862021-11-21T12:34:44ZEfficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system10.1038/s41467-021-26928-y2041-1723https://doaj.org/article/1a017a78f5e242bfab6c97b66db75c862021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26928-yhttps://doaj.org/toc/2041-1723Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E. coli.Le YuWenting ZhouYixuan SheHongmin MaYou-Sheng CaiMing JiangZixin DengNeil P. J. PriceWenqing ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Le Yu Wenting Zhou Yixuan She Hongmin Ma You-Sheng Cai Ming Jiang Zixin Deng Neil P. J. Price Wenqing Chen Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
description	Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E. coli.
format	article
author	Le Yu Wenting Zhou Yixuan She Hongmin Ma You-Sheng Cai Ming Jiang Zixin Deng Neil P. J. Price Wenqing Chen
author_facet	Le Yu Wenting Zhou Yixuan She Hongmin Ma You-Sheng Cai Ming Jiang Zixin Deng Neil P. J. Price Wenqing Chen
author_sort	Le Yu
title	Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
title_short	Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
title_full	Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
title_fullStr	Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
title_full_unstemmed	Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
title_sort	efficient biosynthesis of nucleoside cytokinin angustmycin a containing an unusual sugar system
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1a017a78f5e242bfab6c97b66db75c86
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Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

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