Single-particle mass analysis of intact ribosomes by mass photometry and Orbitrap-based charge detection mass spectrometry
Summary: Standard methods for mass analysis measure ensembles of thousand to millions of molecules. This approach enables analysis of monodisperse recombinant proteins, whereas some heterogeneous protein assemblies pose a significant challenge, whereby co-occurring stoichiometries, sub-complexes, an...
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Main Authors: | Szu-Hsueh Lai, Sem Tamara, Albert J.R. Heck |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Online Access: | https://doaj.org/article/2b24d1a3985d4ec0966e7f67b9c53aee |
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