Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis.
Kaposi sarcoma is a tumor consisting of Kaposi sarcoma herpesvirus (KSHV)-infected tumor cells that express endothelial cell (EC) markers and viral genes like v-cyclin, vFLIP, and LANA. Despite a strong link between KSHV infection and certain neoplasms, de novo virus infection of human primary cells...
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Main Authors: | Sonja Koopal, Johanna H Furuhjelm, Annika Järviluoma, Sari Jäämaa, Pawan Pyakurel, Christel Pussinen, Maria Wirzenius, Peter Biberfeld, Kari Alitalo, Marikki Laiho, Päivi M Ojala |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2007
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Online Access: | https://doaj.org/article/2f23eda7c9764a07baabb81a431641b6 |
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